Detailed information of TA system TA023527

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/LOTUS_5_Limkain_b1(toxin)
• Location: 965428..965999
• Replicon: chromosome
• Accession: NC_011989
• Organism: Agrobacterium vitis S4

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: B9JTA1
• Locus tag: AVI_RS04540
• Protein ID: WP_015915238.1
• Coordinates: 965634..965999 (+)
• Length: 122 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: B9JTA0
• Locus tag: AVI_RS04535
• Protein ID: WP_015915237.1
• Coordinates: 965428..965640 (+)
• Length: 71 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-106)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-40)

Sequences

Toxin

Protein

• Length: 122 a.a.
• Molecular weight: 13576.79 Da
• Isoelectric Point: 7.2785

>T23527 WP_015915238.1 NC_011989:965634-965999 [Agrobacterium vitis S4]
MVKALFDTNILIDFLNGKEPARQELSLYEEKAISMVTWMEVMVGASDENGQATAAFLRSFRCIAIDQTVAERAVALRRAH
RLKLPDAIVWASALAHDMLLVTRDTKDLPGNHPGIRIPYRL

Nucleotide

• Length: 366 bp

>T23527 NC_011989:965634-965999 [Agrobacterium vitis S4]
ATGGTAAAAGCGCTGTTCGATACCAATATCCTGATCGATTTTCTGAACGGCAAGGAACCAGCCAGGCAGGAGCTTTCGCT
TTACGAGGAAAAGGCGATCAGCATGGTGACCTGGATGGAGGTCATGGTTGGCGCATCCGATGAGAACGGGCAAGCGACCG
CTGCTTTTCTTCGCAGTTTTCGCTGCATTGCTATCGATCAGACCGTGGCCGAGCGTGCAGTTGCGTTGAGGCGTGCGCAT
CGGCTGAAACTGCCTGACGCGATTGTCTGGGCAAGTGCTCTGGCCCATGACATGCTGCTGGTAACCCGGGATACCAAGGA
TTTGCCGGGCAATCATCCCGGCATCCGCATTCCCTATCGGCTGTGA

Antitoxin

Protein

• Length: 71 a.a.
• Molecular weight: 8101.19 Da
• Isoelectric Point: 5.0477

>AT23527 WP_015915237.1 NC_011989:965428-965640 [Agrobacterium vitis S4]
MRTLIDLDDDAVVKLDRIARQEKISRAALIRQAVASLLEERQKPDLDHGFGLWKNQPDGLAYQQALRDEW

Nucleotide

• Length: 213 bp

>AT23527 NC_011989:965428-965640 [Agrobacterium vitis S4]
ATGAGAACATTGATCGACCTTGATGACGATGCCGTGGTGAAACTGGACCGGATTGCCCGCCAGGAAAAAATTTCCCGGGC
AGCGTTGATCCGGCAGGCCGTGGCATCGTTGCTGGAAGAACGGCAGAAGCCTGATTTGGATCACGGCTTTGGTCTCTGGA
AAAACCAACCGGATGGCCTTGCCTATCAGCAGGCCCTGCGCGACGAATGGTAA

Structures

Toxin

• AlphaFold DB: B9JTA1

Antitoxin

• AlphaFold DB: B9JTA0