Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 4938504..4939017 Replicon chromosome
Accession NZ_CP091913
Organism Nostoc sp. UHCC 0870

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag L6494_RS20850 Protein ID WP_237989676.1
Coordinates 4938751..4939017 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag L6494_RS20845 Protein ID WP_237989675.1
Coordinates 4938504..4938758 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L6494_RS20820 (L6494_20820) 4933850..4934812 + 963 WP_237989671.1 M48 family metallopeptidase -
L6494_RS20825 (L6494_20825) 4935153..4935578 + 426 WP_237989672.1 hypothetical protein -
L6494_RS20830 (L6494_20830) 4935650..4936207 - 558 WP_237989673.1 Uma2 family endonuclease -
L6494_RS20835 (L6494_20835) 4936310..4937836 + 1527 WP_237989674.1 lysine--tRNA ligase -
L6494_RS20845 (L6494_20845) 4938504..4938758 + 255 WP_237989675.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
L6494_RS20850 (L6494_20850) 4938751..4939017 + 267 WP_237989676.1 Txe/YoeB family addiction module toxin Toxin
L6494_RS20855 (L6494_20855) 4939202..4939816 + 615 WP_237989677.1 hypothetical protein -
L6494_RS20860 (L6494_20860) 4940150..4940263 - 114 WP_237989678.1 F0F1 ATP synthase subunit gamma -
L6494_RS20865 (L6494_20865) 4940272..4940508 - 237 WP_237989679.1 hypothetical protein -
L6494_RS20870 (L6494_20870) 4940496..4940888 - 393 WP_237989680.1 hypothetical protein -
L6494_RS20875 (L6494_20875) 4940930..4941877 - 948 WP_190702096.1 F0F1 ATP synthase subunit gamma -
L6494_RS20880 (L6494_20880) 4942015..4943535 - 1521 WP_190702099.1 F0F1 ATP synthase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10637.10 Da        Isoelectric Point: 8.0050

>T235243 WP_237989676.1 NZ_CP091913:4938751-4939017 [Nostoc sp. UHCC 0870]
MTRKLAWTNEAWNDYLYWQEQDKKTLKRINKLIEATIRLPFEGIGKPEALRENLAGFWSRRIDHTNRLVYAVDDEYLTII
ACRYHYSD

Download         Length: 267 bp

>T235243 NZ_LR134231:1932285-1932388 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9529.81 Da        Isoelectric Point: 4.6135

>AT235243 WP_237989675.1 NZ_CP091913:4938504-4938758 [Nostoc sp. UHCC 0870]
MKIVSFSEARNNLKAVLDRVVEDTDYTIITRRDAEDTVVMSLELFNSLLETVHLLNSPANAAHLERSIAQFKQGKVVERD
LLDD

Download         Length: 255 bp

>AT235243 NZ_LR134231:c1932426-1932155 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References