23514

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 3397198..3397640 Replicon chromosome
Accession NC_011916
Organism Caulobacter crescentus NA1000

Toxin (Protein)


Gene name relE Uniprot ID A0A0H3CB57
Locus tag CCNA_03232 Protein ID YP_002518605.1
Coordinates 3397365..3397640 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0H3CED1
Locus tag CCNA_03231 Protein ID YP_002518604.1
Coordinates 3397198..3397377 (+) Length 60 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCNA_03228 3392256..3394277 - 2022 YP_002518601.1 TPR repeat sulfotransferase family protein -
CCNA_03229 3394360..3395649 - 1290 YP_002518602.1 FAD dependent oxidoreductase -
CCNA_03230 3395725..3397122 - 1398 YP_002518603.1 glutamine synthetase -
CCNA_03988 3397119..3397646 - 528 YP_009020560.1 hypothetical protein -
CCNA_03231 3397198..3397377 + 180 YP_002518604.1 anti-toxin protein relB-4 Antitoxin
CCNA_03232 3397365..3397640 + 276 YP_002518605.1 toxin protein relE4 Toxin
CCNA_03233 3397643..3399046 - 1404 YP_002518606.1 aspartate aminotransferase family protein -
CCNA_03234 3399064..3399813 - 750 YP_002518607.1 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein -
CCNA_03235 3399818..3400963 - 1146 YP_002518608.1 spermidine/putrescine transport ATP-binding protein potA -
CCNA_03236 3401109..3401984 - 876 YP_002518609.1 spermidine/putrescine transport system permease protein potC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10141.74 Da        Isoelectric Point: 11.9574

>T23514 YP_002518605.1 NC_011916:3397365-3397640 [Caulobacter vibrioides NA1000]
VAQVVWTQRAMADVYAIVGHISEQSRPLAAQRLAKRLFDTGASLATYPERGRVSTQGRREIVAISPYVLRYRIVGDRVVI
GSVRHGARRPI

Download         Length: 276 bp

>T23514 NC_011916:3397365-3397640 [Caulobacter vibrioides NA1000]
GTGGCGCAAGTAGTCTGGACCCAACGAGCGATGGCCGATGTTTACGCCATCGTCGGCCATATCTCCGAGCAGTCGCGTCC
TCTCGCGGCCCAGCGCCTGGCCAAGAGGTTGTTCGACACCGGCGCTAGCCTGGCGACCTATCCCGAACGCGGGCGCGTGA
GCACTCAAGGACGGCGTGAGATCGTCGCGATTTCGCCCTACGTTCTGCGCTACCGCATTGTCGGCGACCGTGTCGTCATT
GGCAGCGTACGCCATGGGGCGCGTCGACCTATCTAG

Antitoxin


Download         Length: 60 a.a.        Molecular weight: 6606.17 Da        Isoelectric Point: 3.9689

>AT23514 YP_002518604.1 NC_011916:3397198-3397377 [Caulobacter vibrioides NA1000]
MAEPDPDIFDEDDEAILAADAEADADFEAGRTVPHERVGEWLKTLGTPHQTPPPYSWRK

Download         Length: 180 bp

>AT23514 NC_011916:3397198-3397377 [Caulobacter vibrioides NA1000]
ATGGCCGAGCCTGACCCCGACATCTTCGACGAGGACGATGAAGCGATCCTGGCGGCTGACGCCGAGGCTGACGCCGACTT
CGAAGCCGGTAGAACTGTTCCGCACGAGCGTGTGGGCGAGTGGCTCAAGACGTTGGGCACGCCGCACCAGACACCGCCAC
CATATTCGTGGCGCAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3CB57

Antitoxin

Source ID Structure
AlphaFold DB A0A0H3CED1

References