23510

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 916721..917262 Replicon chromosome
Accession NC_011916
Organism Caulobacter crescentus NA1000

Toxin (Protein)


Gene name relE Uniprot ID A0A0H3C7Y2
Locus tag CCNA_00844 Protein ID YP_002516217.1
Coordinates 916721..917002 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0H3C4R1
Locus tag CCNA_00845 Protein ID YP_002516218.1
Coordinates 916999..917262 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCNA_00841 911803..913419 - 1617 YP_002516214.1 carboxylesterase type B -
CCNA_00842 913509..915233 - 1725 YP_002516215.1 hypothetical protein -
CCNA_00843 915317..916645 - 1329 YP_002516216.1 endo-beta-mannanase -
CCNA_00844 916721..917002 - 282 YP_002516217.1 toxin protein relE1 Toxin
CCNA_00845 916999..917262 - 264 YP_002516218.1 antitoxin protein relB-1 Antitoxin
CCNA_00846 917301..920390 - 3090 YP_002516219.1 proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase PutA -
CCNA_03943 920475..920636 + 162 YP_009020515.1 hypothetical protein -
CCNA_00847 920836..921303 + 468 YP_002516220.1 leucine-responsive regulatory family protein PutR -
CCNA_00848 921330..921494 - 165 YP_002516221.2 leucine-responsive regulatory protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10486.14 Da        Isoelectric Point: 11.7926

>T23510 YP_002516217.1 NC_011916:c917002-916721 [Caulobacter vibrioides NA1000]
MTFTVLVSVRAKRDFNRLIVWLVERDPRAAARLGPLLEAALDSLTEAPSRGRSVGPTTREISIPFGQSAYVIRYRLLGSS
VHVTRIWHGLEQR

Download         Length: 282 bp

>T23510 NC_011916:c917002-916721 [Caulobacter vibrioides NA1000]
TTGACCTTCACGGTTTTGGTATCCGTTCGGGCCAAGAGAGACTTCAACCGTCTCATCGTCTGGCTTGTGGAGCGCGACCC
CCGAGCAGCGGCTAGACTGGGCCCACTTCTGGAGGCCGCCCTCGACAGTTTGACCGAGGCGCCATCGCGAGGTCGCTCGG
TTGGTCCCACCACCCGCGAGATCAGCATTCCTTTTGGTCAGAGCGCCTATGTGATCCGCTACCGGCTCCTCGGCTCCAGC
GTACATGTCACCCGGATCTGGCACGGCCTTGAGCAAAGGTAG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9198.31 Da        Isoelectric Point: 4.2560

>AT23510 YP_002516218.1 NC_011916:c917262-916999 [Caulobacter vibrioides NA1000]
MADGFDIHIDQEQAARLKVVADRLGMSVSEYAVALIDAGLTGAAPKAIDPDPAIDEAIADAIERGDEPAISRDEFRAHIR
RVTAGLG

Download         Length: 264 bp

>AT23510 NC_011916:c917262-916999 [Caulobacter vibrioides NA1000]
ATGGCCGATGGCTTCGACATTCATATCGATCAAGAGCAGGCCGCCCGGCTGAAGGTCGTTGCCGACCGCCTGGGTATGTC
CGTGTCCGAGTACGCCGTTGCGCTGATCGACGCAGGGCTGACAGGCGCGGCGCCTAAAGCGATCGATCCGGACCCCGCCA
TCGACGAGGCCATCGCCGACGCCATCGAGCGGGGCGACGAGCCGGCGATTTCACGCGATGAGTTCCGCGCTCATATACGT
CGCGTGACTGCGGGCCTGGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3C7Y2

Antitoxin

Source ID Structure
AlphaFold DB A0A0H3C4R1

References