Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 4882907..4883441 Replicon chromosome
Accession NZ_CP091861
Organism Flavobacterium bizetiae strain HJ-32-4

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag L0669_RS20125 Protein ID WP_263759674.1
Coordinates 4882907..4883200 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag L0669_RS20130 Protein ID WP_263759675.1
Coordinates 4883193..4883441 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0669_RS20095 (L0669_20095) 4878182..4879432 - 1251 WP_263759668.1 cation:dicarboxylase symporter family transporter -
L0669_RS20105 (L0669_20105) 4879894..4880409 + 516 WP_263759669.1 hypothetical protein -
L0669_RS20110 (L0669_20110) 4880518..4880811 + 294 WP_173972275.1 hypothetical protein -
L0669_RS20115 (L0669_20115) 4880913..4881707 - 795 WP_263759670.1 SDR family oxidoreductase -
L0669_RS20120 (L0669_20120) 4881836..4882210 + 375 WP_263759672.1 helix-turn-helix domain-containing protein -
L0669_RS20125 (L0669_20125) 4882907..4883200 - 294 WP_263759674.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L0669_RS20130 (L0669_20130) 4883193..4883441 - 249 WP_263759675.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
L0669_RS20135 (L0669_20135) 4883695..4884066 - 372 WP_263759676.1 LysM peptidoglycan-binding domain-containing protein -
L0669_RS20140 (L0669_20140) 4884074..4884553 - 480 WP_263759677.1 BON domain-containing protein -
L0669_RS20145 (L0669_20145) 4884715..4885164 - 450 WP_263759678.1 nuclear transport factor 2 family protein -
L0669_RS20150 (L0669_20150) 4885586..4886671 + 1086 WP_263759679.1 DNA polymerase III subunit gamma/tau -
L0669_RS20155 (L0669_20155) 4886947..4887321 + 375 WP_232067407.1 DNA polymerase III -
L0669_RS20160 (L0669_20160) 4887438..4887995 + 558 WP_263759680.1 acetate uptake transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11548.08 Da        Isoelectric Point: 5.1131

>T234901 WP_263759674.1 NZ_CP091861:c4883200-4882907 [Flavobacterium bizetiae]
MAKYYLTNKAVEDLTNIWDYTYDEWSENQADKYYNLLLSSCQEIAENPNLGKKYDNITEKLLGFKSNQHIIFYQIISNTE
VEIIRILHGRMDLKSKF

Download         Length: 294 bp

>T234901 NZ_LR134117:3663442-3663538 [Serratia odorifera]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9171.36 Da        Isoelectric Point: 9.8920

>AT234901 WP_263759675.1 NZ_CP091861:c4883441-4883193 [Flavobacterium bizetiae]
MGRNTSISLGNHFESFIENSLSEGRFKNASEVVRAGLRLLEEEENKLIILKKAVQDGIDSGRAENFDAKKHLESLKAKKR
NG

Download         Length: 249 bp

>AT234901 NZ_LR134117:c3663542-3663420 [Serratia odorifera]
AGACAAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTTAATGCAGGGCTTGTTCAGCCATGCACTTTAAGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References