Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1953371..1953516 Replicon chromosome
Accession NZ_CP091846
Organism Klebsiella pneumoniae strain NB05

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1953407..1953509 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1953371..1953516 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L7D54_RS09485 1948501..1950561 + 2061 WP_004151449.1 oligopeptidase B -
L7D54_RS09490 1950565..1951224 - 660 WP_032425085.1 exodeoxyribonuclease X -
L7D54_RS09495 1951303..1951533 - 231 WP_002911406.1 DNA polymerase III subunit theta -
L7D54_RS09500 1951646..1952020 + 375 WP_004151448.1 CopC domain-containing protein YobA -
L7D54_RS09505 1952024..1952893 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
L7D54_RS09510 1952910..1953248 + 339 WP_016529031.1 YebY family protein -
- 1953371..1953516 - 146 - - Antitoxin
- 1953407..1953509 + 103 - - Toxin
L7D54_RS09515 1953884..1954027 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
L7D54_RS09520 1954132..1955100 - 969 WP_004151446.1 VirK/YbjX family protein -
L7D54_RS09525 1955257..1955910 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
L7D54_RS09530 1955907..1956098 - 192 WP_002911395.1 YebW family protein -
L7D54_RS09535 1956196..1956435 - 240 WP_002911393.1 YebV family protein -
L7D54_RS09540 1956551..1957984 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T234882 NZ_CP091846:1953407-1953509 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT234882 NZ_CP091846:c1953516-1953371 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References