Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1904392..1904537 Replicon chromosome
Accession NZ_CP091813
Organism Klebsiella pneumoniae strain 10MC160002271

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1904428..1904530 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1904392..1904537 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L7F76_RS09420 1899522..1901582 + 2061 WP_004151449.1 oligopeptidase B -
L7F76_RS09425 1901586..1902245 - 660 WP_032425085.1 exodeoxyribonuclease X -
L7F76_RS09430 1902324..1902554 - 231 WP_002911406.1 DNA polymerase III subunit theta -
L7F76_RS09435 1902667..1903041 + 375 WP_004151448.1 CopC domain-containing protein YobA -
L7F76_RS09440 1903045..1903914 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
L7F76_RS09445 1903931..1904269 + 339 WP_016529031.1 YebY family protein -
- 1904392..1904537 - 146 - - Antitoxin
- 1904428..1904530 + 103 - - Toxin
L7F76_RS09450 1904905..1905048 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
L7F76_RS09455 1905153..1906121 - 969 WP_004151446.1 VirK/YbjX family protein -
L7F76_RS09460 1906278..1906931 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
L7F76_RS09465 1906928..1907119 - 192 WP_002911395.1 YebW family protein -
L7F76_RS09470 1907217..1907456 - 240 WP_002911393.1 YebV family protein -
L7F76_RS09475 1907572..1909005 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T234808 NZ_CP091813:1904428-1904530 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT234808 NZ_CP091813:c1904537-1904392 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References