Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3870179..3870960 Replicon chromosome
Accession NZ_CP091779
Organism Enterobacter mori strain ACYC.E9L

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag L6Y89_RS18265 Protein ID WP_010435526.1
Coordinates 3870179..3870670 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag L6Y89_RS18270 Protein ID WP_042713858.1
Coordinates 3870667..3870960 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L6Y89_RS18245 (L6Y89_18245) 3866013..3866705 + 693 WP_218308481.1 response regulator -
L6Y89_RS18250 (L6Y89_18250) 3866821..3868956 - 2136 WP_237844839.1 ornithine decarboxylase -
L6Y89_RS18255 (L6Y89_18255) 3869138..3869851 + 714 WP_108416254.1 DUF554 domain-containing protein -
L6Y89_RS18265 (L6Y89_18265) 3870179..3870670 - 492 WP_010435526.1 GNAT family N-acetyltransferase Toxin
L6Y89_RS18270 (L6Y89_18270) 3870667..3870960 - 294 WP_042713858.1 DUF1778 domain-containing protein Antitoxin
L6Y89_RS18275 (L6Y89_18275) 3871062..3872855 - 1794 WP_237844840.1 hybrid sensor histidine kinase/response regulator -
L6Y89_RS18280 (L6Y89_18280) 3872852..3873484 - 633 WP_237844841.1 response regulator transcription factor -
L6Y89_RS18285 (L6Y89_18285) 3873660..3873974 + 315 WP_010435531.1 lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(87-144)

Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17501.32 Da        Isoelectric Point: 7.7032

>T234778 WP_010435526.1 NZ_CP091779:c3870670-3870179 [Enterobacter mori]
MISAPEPLRAGHILTPFCCGVDSMDNWLKQRAMKNQASGASRTFVCCGGDSNVLAYYSLASSAVTTNTAPGRFRRNMPDP
IPVVVLGRLAVDQSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPMDPMILMVTLGDLV
ASI

Download         Length: 492 bp

>T234778 NZ_LR134082:2618384-2618491 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10941.57 Da        Isoelectric Point: 9.9156

>AT234778 WP_042713858.1 NZ_CP091779:c3870960-3870667 [Enterobacter mori]
MPAANTMAVKRETLNLRIRPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPEAYQEFLARLDQAPAPN
AALRKTMQTPAPWEREK

Download         Length: 294 bp

>AT234778 NZ_LR134082:c2618337-2618271 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References