Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 257977..258573 Replicon chromosome
Accession NZ_CP091779
Organism Enterobacter mori strain ACYC.E9L

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag L6Y89_RS01240 Protein ID WP_237845314.1
Coordinates 258271..258573 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag L6Y89_RS01235 Protein ID WP_042715630.1
Coordinates 257977..258264 (-) Length 96 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L6Y89_RS01230 (L6Y89_01230) 256349..257980 + 1632 WP_237845312.1 Na/Pi cotransporter family protein -
L6Y89_RS01235 (L6Y89_01235) 257977..258264 - 288 WP_042715630.1 putative addiction module antidote protein Antitoxin
L6Y89_RS01240 (L6Y89_01240) 258271..258573 - 303 WP_237845314.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L6Y89_RS01245 (L6Y89_01245) 258771..259643 + 873 WP_237845315.1 23S rRNA pseudouridine(2604) synthase RluF -
L6Y89_RS01250 (L6Y89_01250) 259644..259916 - 273 WP_014830263.1 DUF3811 domain-containing protein -
L6Y89_RS01255 (L6Y89_01255) 259967..260911 - 945 WP_148401251.1 ketopantoate/pantoate/pantothenate transporter PanS -
L6Y89_RS01260 (L6Y89_01260) 261005..262354 - 1350 WP_237845316.1 lysine-sensitive aspartokinase 3 -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 101 a.a.        Molecular weight: 11429.23 Da        Isoelectric Point: 10.0577

>T234765 WP_237845314.1 NZ_CP091779:c258573-258271 [Enterobacter mori]
MKEIVQTESFRRWEQNLKDRRAKTIIASRLFRLANGLAGDVKPVGEGISELRIHFGPSYRIYFKDQGNCIIVLLCGGDKS
SQARDILMAKMLSNVSQWQE

Download         Length: 303 bp

>T234765 NZ_LR134080:c4557790-4557617 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10131.62 Da        Isoelectric Point: 5.7807

>AT234765 WP_042715630.1 NZ_CP091779:c258264-257977 [Enterobacter mori]
MHKLTPYDPANALVDDEEIAVFMADALETGDSAYIAKTLGVIARAKGMSTISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGLGLTIKPTGD

Download         Length: 288 bp

>AT234765 NZ_LR134080:c4558114-4557818 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCTTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CTTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References