Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumAB/COG3657-dnstrm_HI1420 |
Location | 257977..258573 | Replicon | chromosome |
Accession | NZ_CP091779 | ||
Organism | Enterobacter mori strain ACYC.E9L |
Toxin (Protein)
Gene name | PumA | Uniprot ID | - |
Locus tag | L6Y89_RS01240 | Protein ID | WP_237845314.1 |
Coordinates | 258271..258573 (-) | Length | 101 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | - |
Locus tag | L6Y89_RS01235 | Protein ID | WP_042715630.1 |
Coordinates | 257977..258264 (-) | Length | 96 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
L6Y89_RS01230 (L6Y89_01230) | 256349..257980 | + | 1632 | WP_237845312.1 | Na/Pi cotransporter family protein | - |
L6Y89_RS01235 (L6Y89_01235) | 257977..258264 | - | 288 | WP_042715630.1 | putative addiction module antidote protein | Antitoxin |
L6Y89_RS01240 (L6Y89_01240) | 258271..258573 | - | 303 | WP_237845314.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
L6Y89_RS01245 (L6Y89_01245) | 258771..259643 | + | 873 | WP_237845315.1 | 23S rRNA pseudouridine(2604) synthase RluF | - |
L6Y89_RS01250 (L6Y89_01250) | 259644..259916 | - | 273 | WP_014830263.1 | DUF3811 domain-containing protein | - |
L6Y89_RS01255 (L6Y89_01255) | 259967..260911 | - | 945 | WP_148401251.1 | ketopantoate/pantoate/pantothenate transporter PanS | - |
L6Y89_RS01260 (L6Y89_01260) | 261005..262354 | - | 1350 | WP_237845316.1 | lysine-sensitive aspartokinase 3 | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11429.23 Da Isoelectric Point: 10.0577
>T234765 WP_237845314.1 NZ_CP091779:c258573-258271 [Enterobacter mori]
MKEIVQTESFRRWEQNLKDRRAKTIIASRLFRLANGLAGDVKPVGEGISELRIHFGPSYRIYFKDQGNCIIVLLCGGDKS
SQARDILMAKMLSNVSQWQE
MKEIVQTESFRRWEQNLKDRRAKTIIASRLFRLANGLAGDVKPVGEGISELRIHFGPSYRIYFKDQGNCIIVLLCGGDKS
SQARDILMAKMLSNVSQWQE
Download Length: 303 bp
>T234765 NZ_LR134080:c4557790-4557617 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG
Antitoxin
Download Length: 96 a.a. Molecular weight: 10131.62 Da Isoelectric Point: 5.7807
>AT234765 WP_042715630.1 NZ_CP091779:c258264-257977 [Enterobacter mori]
MHKLTPYDPANALVDDEEIAVFMADALETGDSAYIAKTLGVIARAKGMSTISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGLGLTIKPTGD
MHKLTPYDPANALVDDEEIAVFMADALETGDSAYIAKTLGVIARAKGMSTISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGLGLTIKPTGD
Download Length: 288 bp
>AT234765 NZ_LR134080:c4558114-4557818 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCTTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CTTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCTTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CTTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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