Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2147533..2147804 Replicon chromosome
Accession NZ_CP091756
Organism Escherichia coli strain LC-1302-2020

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2147663..2147766 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2147533..2147804 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L6507_RS10290 2144088..2144750 - 663 WP_000944256.1 exodeoxyribonuclease X -
L6507_RS10295 2144774..2145430 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
L6507_RS10300 2145532..2145762 - 231 WP_000916763.1 DNA polymerase III subunit theta -
L6507_RS10305 2145901..2146275 + 375 WP_000168747.1 CopC domain-containing protein YobA -
L6507_RS10310 2146279..2147151 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
L6507_RS10315 2147164..2147505 + 342 WP_000976476.1 YebY family protein -
- 2147533..2147804 - 272 - - Antitoxin
- 2147663..2147766 + 104 - - Toxin
L6507_RS10320 2147901..2148557 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
L6507_RS10325 2148558..2148749 - 192 WP_000457842.1 YebW family protein -
L6507_RS10330 2148854..2149090 - 237 WP_001295499.1 YebV family protein -
L6507_RS10335 2149208..2150647 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T234705 NZ_CP091756:2147663-2147766 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT234705 NZ_CP091756:c2147804-2147533 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References