Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1581900..1582441 Replicon chromosome
Accession NC_011753
Organism Vibrio splendidus LGP32

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag VS_RS06780 Protein ID WP_012603901.1
Coordinates 1581900..1582202 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag VS_RS06785 Protein ID WP_012603902.1
Coordinates 1582199..1582441 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VS_RS21945 1577045..1577413 + 369 WP_049779137.1 hypothetical protein -
VS_RS06755 1577957..1578652 + 696 WP_157863193.1 hypothetical protein -
VS_RS06760 1578665..1579141 + 477 WP_012603897.1 hypothetical protein -
VS_RS06765 1579288..1580322 + 1035 WP_012603898.1 DUF4062 domain-containing protein -
VS_RS06770 1580452..1581402 + 951 WP_157863194.1 hypothetical protein -
VS_RS06775 1581399..1581875 + 477 WP_012603900.1 SocA family protein -
VS_RS06780 1581900..1582202 - 303 WP_012603901.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
VS_RS06785 1582199..1582441 - 243 WP_012603902.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
VS_RS06790 1582810..1583298 - 489 WP_041472979.1 transposase -
VS_RS06795 1584836..1585207 - 372 WP_041472799.1 helix-turn-helix domain-containing protein -
VS_RS06800 1585338..1586470 + 1133 Protein_1301 hypothetical protein -
VS_RS06805 1586480..1586755 + 276 WP_012603910.1 G5P family DNA-binding protein -
VS_RS06810 1586755..1587195 + 441 WP_012603911.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11809.61 Da        Isoelectric Point: 10.3381

>T23442 WP_012603901.1 NC_011753:c1582202-1581900 [Vibrio atlanticus]
MTPFQLTNKAKSDLKDIALFTERRWGRKQRNVYIRQFDATFGRLAENPELGKTCDEIRPDYRKFPLASHVIFYQKTNNQP
TLIIRILHKSMDVSSIFDMS

Download         Length: 303 bp

>T23442 NC_011753:c1582202-1581900 [Vibrio atlanticus]
ATGACGCCTTTTCAGCTCACGAACAAGGCTAAGTCCGATCTAAAAGACATAGCCTTATTTACTGAGCGTCGCTGGGGCCG
CAAGCAACGAAATGTCTATATCAGACAATTCGATGCCACATTTGGGCGCTTAGCGGAAAATCCAGAGCTAGGAAAAACTT
GCGATGAAATCAGACCAGATTATCGAAAATTCCCGCTTGCCAGTCATGTCATTTTCTACCAGAAAACGAATAACCAACCT
ACTCTAATCATCCGAATTTTACATAAAAGTATGGATGTTAGCTCAATCTTTGACATGTCATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8958.94 Da        Isoelectric Point: 4.2340

>AT23442 WP_012603902.1 NC_011753:c1582441-1582199 [Vibrio atlanticus]
MAKNTSITLGEHFEGFIATQIQSGRYGSASEVIRSALRLLETQETKMDTLRQLLVEGENSGIADYDLDAFFNELDSEEKK

Download         Length: 243 bp

>AT23442 NC_011753:c1582441-1582199 [Vibrio atlanticus]
ATGGCGAAGAATACAAGCATTACCTTGGGTGAACACTTTGAGGGCTTTATTGCGACTCAAATCCAAAGTGGTCGTTATGG
CTCGGCCAGTGAGGTGATCCGCTCGGCGCTACGTTTACTTGAAACCCAAGAGACGAAGATGGATACGTTACGACAGTTGC
TCGTGGAAGGTGAAAACAGTGGAATCGCGGATTACGACCTCGATGCTTTCTTTAACGAACTCGACAGTGAAGAGAAGAAA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References