Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 836943..837582 Replicon chromosome
Accession NZ_CP091647
Organism Burkholderia aenigmatica strain CMCC(B)23010

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag L3V59_RS21890 Protein ID WP_237435066.1
Coordinates 836943..837359 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag L3V59_RS21895 Protein ID WP_089442454.1
Coordinates 837346..837582 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3V59_RS21865 (L3V59_21865) 832083..833003 - 921 WP_175219630.1 enoyl-CoA hydratase -
L3V59_RS21870 (L3V59_21870) 833012..833809 - 798 WP_237435063.1 ketoacid CoA transferase -
L3V59_RS21875 (L3V59_21875) 833821..834714 - 894 WP_122947164.1 CoA-transferase -
L3V59_RS21880 (L3V59_21880) 834724..835620 - 897 WP_237435064.1 VOC family protein -
L3V59_RS21885 (L3V59_21885) 835971..836807 - 837 WP_237435065.1 FkbM family methyltransferase -
L3V59_RS21890 (L3V59_21890) 836943..837359 - 417 WP_237435066.1 type II toxin-antitoxin system VapC family toxin Toxin
L3V59_RS21895 (L3V59_21895) 837346..837582 - 237 WP_089442454.1 DNA-binding protein Antitoxin
L3V59_RS21900 (L3V59_21900) 837977..838630 - 654 WP_237435067.1 hypothetical protein -
L3V59_RS21905 (L3V59_21905) 840316..841599 + 1284 WP_237435068.1 hypothetical protein -
L3V59_RS21910 (L3V59_21910) 841659..842432 - 774 WP_237435069.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15367.55 Da        Isoelectric Point: 6.6442

>T234199 WP_237435066.1 NZ_CP091647:c837359-836943 [Burkholderia aenigmatica]
VYLIDTNVISEIRKGKRTNHGVRAFFRQAAADASPLYLSVVTVAELRRGVDLIRHRGDHPQASALESWMATILAGYAPNI
LPVDIEISQMWGHLRVPDPTHELDQLIAATALINDLTVVTRNVDDFSRTGVRLLNPFD

Download         Length: 417 bp

>T234199 NZ_LR027873:c915107-914919 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTAGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8554.60 Da        Isoelectric Point: 5.7974

>AT234199 WP_089442454.1 NZ_CP091647:c837582-837346 [Burkholderia aenigmatica]
MANLLVRNVDDSIVQSLREQAAANGRSAEAEHRAILAAALGRPKRKTFAQVLMSMPDVGDDADFQRVQDSGEARRVFD

Download         Length: 237 bp

>AT234199 NZ_LR027873:c915396-915136 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References