Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3864959..3865104 Replicon chromosome
Accession NZ_CP091601
Organism Klebsiella pneumoniae strain Nord77_R886

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3864966..3865068 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3864959..3865104 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L5469_RS20110 3860490..3861923 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
L5469_RS20115 3862039..3862278 + 240 WP_002911393.1 YebV family protein -
L5469_RS20120 3862376..3862567 + 192 WP_002911395.1 YebW family protein -
L5469_RS20125 3862564..3863217 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
L5469_RS20130 3863374..3864342 + 969 WP_004151446.1 VirK/YbjX family protein -
L5469_RS20135 3864447..3864590 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3864959..3865104 + 146 - - Antitoxin
- 3864966..3865068 - 103 - - Toxin
L5469_RS20140 3865227..3865565 - 339 WP_002911404.1 YebY family protein -
L5469_RS20145 3865582..3866451 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
L5469_RS20150 3866455..3866829 - 375 WP_004151448.1 CopC domain-containing protein YobA -
L5469_RS20155 3866942..3867172 + 231 WP_002911406.1 DNA polymerase III subunit theta -
L5469_RS20160 3867251..3867910 + 660 WP_043906809.1 exodeoxyribonuclease X -
L5469_RS20165 3867914..3869974 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3855076..3938158 83082


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T233946 NZ_CP091601:c3865068-3864966 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT233946 NZ_CP091601:3864959-3865104 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References