Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3021682..3021827 Replicon chromosome
Accession NZ_CP091594
Organism Klebsiella pneumoniae strain Nord5-1_R48

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3021718..3021820 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3021682..3021827 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L5467_RS17700 3016812..3018872 + 2061 WP_004151449.1 oligopeptidase B -
L5467_RS17705 3018876..3019535 - 660 WP_002911407.1 exodeoxyribonuclease X -
L5467_RS17710 3019614..3019844 - 231 WP_002911406.1 DNA polymerase III subunit theta -
L5467_RS17715 3019957..3020331 + 375 WP_039819395.1 CopC domain-containing protein YobA -
L5467_RS17720 3020335..3021204 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
L5467_RS17725 3021221..3021559 + 339 WP_002911404.1 YebY family protein -
- 3021682..3021827 - 146 - - Antitoxin
- 3021718..3021820 + 103 - - Toxin
L5467_RS17730 3022196..3022339 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
L5467_RS17735 3022444..3023412 - 969 WP_014907334.1 VirK/YbjX family protein -
L5467_RS17740 3023569..3024222 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
L5467_RS17745 3024219..3024410 - 192 WP_002911395.1 YebW family protein -
L5467_RS17750 3024508..3024747 - 240 WP_002911393.1 YebV family protein -
L5467_RS17755 3024863..3026296 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T233925 NZ_CP091594:3021718-3021820 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT233925 NZ_CP091594:c3021827-3021682 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References