Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3760313..3760458 Replicon chromosome
Accession NZ_CP091582
Organism Klebsiella pneumoniae strain Nord9_R85

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3760349..3760451 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3760313..3760458 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L5468_RS18430 (L5468_18430) 3755442..3757502 + 2061 WP_004151449.1 oligopeptidase B -
L5468_RS18435 (L5468_18435) 3757506..3758165 - 660 WP_234283381.1 exodeoxyribonuclease X -
L5468_RS18440 (L5468_18440) 3758244..3758474 - 231 WP_064181481.1 DNA polymerase III subunit theta -
L5468_RS18445 (L5468_18445) 3758587..3758961 + 375 WP_237437219.1 CopC domain-containing protein YobA -
L5468_RS18450 (L5468_18450) 3758965..3759834 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
L5468_RS18455 (L5468_18455) 3759851..3760189 + 339 WP_002911404.1 YebY family protein -
- 3760313..3760458 - 146 - - Antitoxin
- 3760349..3760451 + 103 - - Toxin
L5468_RS18460 (L5468_18460) 3760826..3760969 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
L5468_RS18465 (L5468_18465) 3761074..3762042 - 969 WP_184856114.1 VirK/YbjX family protein -
L5468_RS18470 (L5468_18470) 3762199..3762852 + 654 WP_237437220.1 protein-serine/threonine phosphatase -
L5468_RS18475 (L5468_18475) 3762849..3763040 - 192 WP_002911395.1 YebW family protein -
L5468_RS18480 (L5468_18480) 3763138..3763377 - 240 WP_002911393.1 YebV family protein -
L5468_RS18485 (L5468_18485) 3763493..3764926 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T233902 NZ_CP091582:3760349-3760451 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT233902 NZ_CP091582:c3760458-3760313 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References