Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-DnaT |
| Location | 56166..56688 | Replicon | 2 plasmid p2-mcr |
| Accession | NZ_CP091575 | ||
| Organism | Salmonella enterica strain | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | U9YLU1 |
| Locus tag | INN74_RS26430 | Protein ID | WP_000638823.1 |
| Coordinates | 56166..56447 (-) | Length | 94 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | U9Y7J1 |
| Locus tag | INN74_RS26435 | Protein ID | WP_000121741.1 |
| Coordinates | 56437..56688 (-) | Length | 84 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| INN74_RS26395 (INN74_26395) | 52315..52635 | - | 321 | WP_000362080.1 | VirB3 family type IV secretion system protein | - |
| INN74_RS26400 (INN74_26400) | 52706..52996 | - | 291 | WP_000865479.1 | conjugal transfer protein | - |
| INN74_RS26405 (INN74_26405) | 52996..53580 | - | 585 | WP_001177114.1 | lytic transglycosylase domain-containing protein | - |
| INN74_RS26410 (INN74_26410) | 53601..53999 | - | 399 | WP_001153665.1 | hypothetical protein | - |
| INN74_RS26415 (INN74_26415) | 54118..54555 | - | 438 | WP_000539665.1 | type IV pilus biogenesis protein PilM | - |
| INN74_RS26420 (INN74_26420) | 54561..55796 | - | 1236 | WP_015059538.1 | TcpQ domain-containing protein | - |
| INN74_RS26425 (INN74_26425) | 55799..56098 | - | 300 | WP_000835764.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| INN74_RS26430 (INN74_26430) | 56166..56447 | - | 282 | WP_000638823.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| INN74_RS26435 (INN74_26435) | 56437..56688 | - | 252 | WP_000121741.1 | hypothetical protein | Antitoxin |
| INN74_RS26440 (INN74_26440) | 56788..57423 | - | 636 | WP_015059536.1 | hypothetical protein | - |
| INN74_RS26445 (INN74_26445) | 57504..58280 | + | 777 | WP_236919128.1 | DUF5710 domain-containing protein | - |
| INN74_RS26450 (INN74_26450) | 58503..58727 | - | 225 | WP_065304445.1 | EexN family lipoprotein | - |
| INN74_RS26455 (INN74_26455) | 58736..59380 | - | 645 | WP_065304453.1 | type IV secretion system protein | - |
| INN74_RS26460 (INN74_26460) | 59386..60381 | - | 996 | WP_065304446.1 | type IV secretion system protein | - |
| INN74_RS26465 (INN74_26465) | 60385..60642 | - | 258 | WP_000739144.1 | hypothetical protein | - |
| INN74_RS26470 (INN74_26470) | 60639..60941 | - | 303 | WP_065304447.1 | hypothetical protein | - |
| INN74_RS26475 (INN74_26475) | 61156..61464 | - | 309 | WP_236492988.1 | hypothetical protein | - |
| INN74_RS26480 (INN74_26480) | 61511..61681 | - | 171 | WP_044069355.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Mobilizable plasmid | mcr-1.1 | - | 1..65271 | 65271 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10945.79 Da Isoelectric Point: 10.4997
>T233889 WP_000638823.1 NZ_CP091575:c56447-56166 [Salmonella enterica]
MIYELAFDHRALKEWQKLGHTVREQFKKKLSERLINPRVPAAKLHGHTDRYKIKLRASGYRLVYQVIDEKVVLLVISVGK
REGSDVYHMADTR
MIYELAFDHRALKEWQKLGHTVREQFKKKLSERLINPRVPAAKLHGHTDRYKIKLRASGYRLVYQVIDEKVVLLVISVGK
REGSDVYHMADTR
Download Length: 282 bp
>T233889 NZ_LN847264:c980032-979535 [Pseudomonas sp. CCOS 191]
ATGACTGAAACGAGGCGCAAACCTCTATGCGTGCATGGCTGGAGTGTGTTCGCCCACCCCCTCTTTCTCGACAAGCTCGA
GGCGCTCATCGATGAAGTCGAAGTGCTTCAGAGGAAAGATCCGGTCGGGTATGTGAAGAAAAATGCGGCAAAACGATTGA
AGGCCATCAGACGCTTGGCCTTCGACGTCATTGCCCAGGCGCCCGGCAACCCGGACCATCGCATGGGCGGCACACTGGGC
GCGGAACACAAGCACTGGTTCCGTGCCAAGTTCTTCCAGCAATATCGTTTGTTTTTCCGTTATCACGCATCCAGCAAGAT
CATCGTGCTGGCGTGGGTGAATGATGACAACAGCAAACGCGCTTACGAGAGCAGCGATGACGCCTACCGAGTGTTCCGCC
GCATGCTGGGTAACGGACACCCGCCTGACGACTGGGATCAGCTGTTGCAGGAAGCTGCTGCGGCAACAGCCCGATTCAAC
GCCACCCTCAAGCGCTGA
ATGACTGAAACGAGGCGCAAACCTCTATGCGTGCATGGCTGGAGTGTGTTCGCCCACCCCCTCTTTCTCGACAAGCTCGA
GGCGCTCATCGATGAAGTCGAAGTGCTTCAGAGGAAAGATCCGGTCGGGTATGTGAAGAAAAATGCGGCAAAACGATTGA
AGGCCATCAGACGCTTGGCCTTCGACGTCATTGCCCAGGCGCCCGGCAACCCGGACCATCGCATGGGCGGCACACTGGGC
GCGGAACACAAGCACTGGTTCCGTGCCAAGTTCTTCCAGCAATATCGTTTGTTTTTCCGTTATCACGCATCCAGCAAGAT
CATCGTGCTGGCGTGGGTGAATGATGACAACAGCAAACGCGCTTACGAGAGCAGCGATGACGCCTACCGAGTGTTCCGCC
GCATGCTGGGTAACGGACACCCGCCTGACGACTGGGATCAGCTGTTGCAGGAAGCTGCTGCGGCAACAGCCCGATTCAAC
GCCACCCTCAAGCGCTGA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9223.38 Da Isoelectric Point: 3.9823
>AT233889 WP_000121741.1 NZ_CP091575:c56688-56437 [Salmonella enterica]
MSYQILTTTAASITDLKKNPMGTVAEGEGDAVAILNRNEPAFYCVPPELYAYYRELAEDAELNAIADERMKNPDIVRVNL
DDL
MSYQILTTTAASITDLKKNPMGTVAEGEGDAVAILNRNEPAFYCVPPELYAYYRELAEDAELNAIADERMKNPDIVRVNL
DDL
Download Length: 252 bp
>AT233889 NZ_LN847264:c980355-980029 [Pseudomonas sp. CCOS 191]
ATGGCTACTACCTTCGAAGCGGAATCGACCCTGACCGAGCGCTACCAGACAACGGTCCCCGAAACCGTTCGCCGCGCGTT
GGGCCTGAAAAAGCGTGACAAGATTCACTACTCGATCCGCCCTGACGGAGCAGTGATACTGACCCGCGCAGAGACAGCCG
AGGAAGACCCTGCCGTGGGGCAGTTCCTCGAATTCCTGGAACGGGATATCGCCACGAACCCGCAACGTTTGAAGGTTGTC
GATGCAGAGCTCGTCGCTCGCCTGGATGCACTGGTTGGCGACGTTGAAATCGATCTCGATCAACCTCTATCGGCGGACGA
TGAATGA
ATGGCTACTACCTTCGAAGCGGAATCGACCCTGACCGAGCGCTACCAGACAACGGTCCCCGAAACCGTTCGCCGCGCGTT
GGGCCTGAAAAAGCGTGACAAGATTCACTACTCGATCCGCCCTGACGGAGCAGTGATACTGACCCGCGCAGAGACAGCCG
AGGAAGACCCTGCCGTGGGGCAGTTCCTCGAATTCCTGGAACGGGATATCGCCACGAACCCGCAACGTTTGAAGGTTGTC
GATGCAGAGCTCGTCGCTCGCCTGGATGCACTGGTTGGCGACGTTGAAATCGATCTCGATCAACCTCTATCGGCGGACGA
TGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|