Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafN(antitoxin)
Location 97330..97895 Replicon chromosome
Accession NC_011744
Organism Vibrio splendidus LGP32

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag VS_RS15215 Protein ID WP_012600095.1
Coordinates 97608..97895 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag VS_RS15210 Protein ID WP_012600094.1
Coordinates 97330..97608 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VS_RS22335 92616..92798 - 183 Protein_74 IS110 family transposase -
VS_RS15185 92897..93433 + 537 WP_012600089.1 hypothetical protein -
VS_RS15190 93645..93809 - 165 Protein_76 IS110 family transposase -
VS_RS15195 93893..94486 + 594 WP_012600091.1 hypothetical protein -
VS_RS22340 94865..96601 + 1737 WP_012600092.1 S-type pyocin domain-containing protein -
VS_RS15205 96598..96993 + 396 WP_012600093.1 hypothetical protein -
VS_RS15210 97330..97608 + 279 WP_012600094.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
VS_RS15215 97608..97895 + 288 WP_012600095.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
VS_RS15220 98076..98777 + 702 WP_041473199.1 lipoate--protein ligase -
VS_RS15225 98945..99784 - 840 WP_012600097.1 SDR family NAD(P)-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-74)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10853.53 Da        Isoelectric Point: 4.8254

>T23384 WP_012600095.1 NC_011744:97608-97895 [Vibrio atlanticus]
VEVVWSPLALEKLGDAAEFIALDNPVAAKNWINEAFDKTELLGTMPEIGRMVPEMPHTHYREVLFGHYRIIYSLGIEIRI
LTVRNCRQTLTESDV

Download         Length: 288 bp

>T23384 NC_011744:97608-97895 [Vibrio atlanticus]
GTGGAAGTAGTTTGGTCTCCATTAGCTCTTGAAAAGCTTGGTGATGCTGCTGAGTTCATTGCATTAGATAACCCCGTTGC
TGCGAAAAATTGGATTAACGAAGCTTTCGATAAAACTGAATTGCTTGGAACTATGCCAGAAATAGGGCGAATGGTTCCTG
AAATGCCACATACACACTACCGCGAGGTTTTGTTTGGTCACTATCGTATTATCTATAGTCTGGGGATTGAAATTCGTATT
CTAACTGTCCGTAATTGTCGACAGACTTTAACTGAAAGTGACGTGTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10264.77 Da        Isoelectric Point: 5.1548

>AT23384 WP_012600094.1 NC_011744:97330-97608 [Vibrio atlanticus]
MSRIHLDQDIQPLSEFRAGVTSFIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRAAETQLASGLGVSN
EDARAQVLGRIK

Download         Length: 279 bp

>AT23384 NC_011744:97330-97608 [Vibrio atlanticus]
ATGAGCCGTATTCATCTTGACCAAGATATTCAGCCCCTTTCTGAGTTTCGTGCTGGTGTAACCTCATTTATCAAACAAAT
TAATGAAACCCGTCGCCCACTCGTAATAACACAGCGAGGTAAAGGTGTTGCTGTTGTCCTTGATGTTGCTGAATATGAAG
CTATGCAGGAAAAAATCGAGTTGCTTGAAGAAATGAGAGCAGCTGAGACGCAACTCGCTTCTGGTTTAGGAGTGTCTAAT
GAAGATGCACGCGCTCAAGTTTTAGGGCGAATCAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References