Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1878189..1878457 Replicon chromosome
Accession NC_011742
Organism Escherichia coli S88

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1878227..1878329 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1878189..1878457 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECS88_RS10765 1875346..1876785 + 1440 WP_001350670.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ECS88_RS10770 1876903..1877139 + 237 WP_001295499.1 DUF1480 family protein -
ECS88_RS10775 1877244..1877435 + 192 WP_001296140.1 YebW family protein -
ECS88_RS10780 1877436..1878092 - 657 WP_000812741.1 protein-serine/threonine phosphatase -
- 1878189..1878457 + 269 - - Antitoxin
- 1878227..1878329 - 103 - - Toxin
ECS88_RS10785 1878487..1878828 - 342 WP_000984819.1 YebY family protein -
ECS88_RS10790 1878841..1879713 - 873 WP_000879320.1 copper homeostasis membrane protein CopD -
ECS88_RS10795 1879717..1880091 - 375 WP_000168747.1 CopC domain-containing protein YobA -
ECS88_RS10800 1880230..1880460 + 231 WP_000916763.1 DNA polymerase III subunit theta -
ECS88_RS10805 1880562..1881218 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
ECS88_RS10810 1881241..1881903 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T23360 NC_011742:c1878329-1878227 [Escherichia coli S88]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT23360 NC_011742:1878189-1878457 [Escherichia coli S88]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References