Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | stbE-relB/ParE-YafN |
| Location | 1609868..1610405 | Replicon | chromosome |
| Accession | NZ_CP091519 | ||
| Organism | Alysiella crassa strain S6 | ||
Toxin (Protein)
| Gene name | stbE | Uniprot ID | A0A376BTQ8 |
| Locus tag | LVJ80_RS08400 | Protein ID | WP_034296434.1 |
| Coordinates | 1609868..1610164 (-) | Length | 99 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | LVJ80_RS08405 | Protein ID | WP_244772895.1 |
| Coordinates | 1610154..1610405 (-) | Length | 84 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LVJ80_RS08370 (LVJ80_08370) | 1605680..1605979 | + | 300 | WP_034296419.1 | hypothetical protein | - |
| LVJ80_RS08375 (LVJ80_08375) | 1606014..1606691 | + | 678 | WP_034296421.1 | hypothetical protein | - |
| LVJ80_RS08380 (LVJ80_08380) | 1606754..1606951 | + | 198 | WP_034296424.1 | hypothetical protein | - |
| LVJ80_RS08385 (LVJ80_08385) | 1606948..1607844 | + | 897 | WP_034296427.1 | hypothetical protein | - |
| LVJ80_RS08390 (LVJ80_08390) | 1607861..1608136 | + | 276 | WP_034296429.1 | pyocin activator PrtN family protein | - |
| LVJ80_RS08395 (LVJ80_08395) | 1608177..1609340 | - | 1164 | WP_034296432.1 | tyrosine-type recombinase/integrase | - |
| LVJ80_RS08400 (LVJ80_08400) | 1609868..1610164 | - | 297 | WP_034296434.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LVJ80_RS08405 (LVJ80_08405) | 1610154..1610405 | - | 252 | WP_244772895.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
| LVJ80_RS08410 (LVJ80_08410) | 1610662..1611222 | - | 561 | WP_034296439.1 | adenine phosphoribosyltransferase | - |
| LVJ80_RS08415 (LVJ80_08415) | 1611252..1612175 | - | 924 | WP_034296442.1 | homoserine kinase | - |
| LVJ80_RS08420 (LVJ80_08420) | 1612425..1613039 | - | 615 | WP_034296444.1 | lytic transglycosylase domain-containing protein | - |
| LVJ80_RS08425 (LVJ80_08425) | 1613174..1613467 | - | 294 | WP_034296446.1 | hypothetical protein | - |
| LVJ80_RS08430 (LVJ80_08430) | 1613592..1614659 | - | 1068 | WP_034296449.1 | uroporphyrinogen decarboxylase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1569733..1611222 | 41489 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11506.07 Da Isoelectric Point: 9.6747
>T233472 WP_034296434.1 NZ_CP091519:c1610164-1609868 [Alysiella crassa]
MSYELAFYPSAQREWDKLDNSIKQQFKNVLARRLENPRVPSAALHNMPDCYKIKLRRAGYRLVYHVDDNVIVVSVISVGK
RERNAVYDTAQNRLHNDE
MSYELAFYPSAQREWDKLDNSIKQQFKNVLARRLENPRVPSAALHNMPDCYKIKLRRAGYRLVYHVDDNVIVVSVISVGK
RERNAVYDTAQNRLHNDE
Download Length: 297 bp
>T233472 NZ_HG941718:2278227-2278601 [Escherichia coli O25b:H4-ST131]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGATACTGCTGTC
CCGACTGCTGGACCAGCACTATGGCCTCACACTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCAGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGATACTGCTGTC
CCGACTGCTGGACCAGCACTATGGCCTCACACTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCAGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9450.75 Da Isoelectric Point: 4.1677
>AT233472 WP_244772895.1 NZ_CP091519:c1610405-1610154 [Alysiella crassa]
MMMNAVLADYAVSVTDLKRNYATIINEAVGAVAVLNHNRPEAYLVPAAYYEQLMDYLEDLEDAEIVRQRMNNEKSVKVNL
DEL
MMMNAVLADYAVSVTDLKRNYATIINEAVGAVAVLNHNRPEAYLVPAAYYEQLMDYLEDLEDAEIVRQRMNNEKSVKVNL
DEL
Download Length: 252 bp
>AT233472 NZ_HG941718:2277770-2278138 [Escherichia coli O25b:H4-ST131]
GTGTCAGACAAACTCCATGAGACAAATTATCCCGACGACCATAACGACCGCCTCTGGTGGGGACTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCAAAGCCGATACCCTCAGCAGTTG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAATGAAAAATTAA
GTGTCAGACAAACTCCATGAGACAAATTATCCCGACGACCATAACGACCGCCTCTGGTGGGGACTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCAAAGCCGATACCCTCAGCAGTTG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAATGAAAAATTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|