Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 647148..647698 Replicon chromosome
Accession NZ_CP091518
Organism Kingella kingae strain 4177/66

Toxin (Protein)


Gene name relE Uniprot ID F5S5C3
Locus tag LVJ79_RS03505 Protein ID WP_003785639.1
Coordinates 647429..647698 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID F5S5C2
Locus tag LVJ79_RS03500 Protein ID WP_003785638.1
Coordinates 647148..647432 (+) Length 95 a.a.

Genomic Context

LVJ79_RS03470LVJ79_RS03475LVJ79_RS03480LVJ79_RS03485LVJ79_RS03490LVJ79_RS03495LVJ79_RS03500LVJ79_RS03505LVJ79_RS03510LVJ79_RS03515LVJ79_RS03520LVJ79_RS03525LVJ79_RS03530LVJ79_RS03535LVJ79_RS03540LVJ79_RS03465
Location: 644199..644552 (354 bp)
Type: Others
Protein ID: WP_003785632.1
Location: 644533..645063 (531 bp)
Type: Others
Protein ID: WP_003785633.1
Location: 645060..645377 (318 bp)
Type: Others
Protein ID: WP_003785634.1
Location: 645583..645801 (219 bp)
Type: Others
Protein ID: WP_003785635.1
Location: 645788..646219 (432 bp)
Type: Others
Protein ID: WP_003785636.1
Location: 646223..646957 (735 bp)
Type: Others
Protein ID: WP_003785637.1
Location: 647148..647432 (285 bp)
Type: Antitoxin
Protein ID: WP_003785638.1
Location: 647429..647698 (270 bp)
Type: Toxin
Protein ID: WP_003785639.1
Location: 647857..648465 (609 bp)
Type: Others
Protein ID: WP_003785640.1
Location: 648462..648797 (336 bp)
Type: Others
Protein ID: WP_003785641.1
Location: 648794..649690 (897 bp)
Type: Others
Protein ID: WP_003785643.1
Location: 649687..650268 (582 bp)
Type: Others
Protein ID: WP_003785645.1
Location: 650286..651686 (1401 bp)
Type: Others
Protein ID: WP_111694425.1
Location: 651699..651908 (210 bp)
Type: Others
Protein ID: WP_032133698.1
Location: 651853..652209 (357 bp)
Type: Others
Protein ID: WP_003789002.1
Location: 643279..644136 (858 bp)
Type: Others
Protein ID: WP_003785631.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LVJ79_RS03465 (LVJ79_03465)643279..644136-858WP_003785631.1tyrosine-type recombinase/integrase-
LVJ79_RS03470 (LVJ79_03470)644199..644552+354WP_003785632.1phage holin family protein-
LVJ79_RS03475 (LVJ79_03475)644533..645063+531WP_003785633.1glycoside hydrolase family 108 protein-
LVJ79_RS03480 (LVJ79_03480)645060..645377+318WP_003785634.1hypothetical protein-
LVJ79_RS03485 (LVJ79_03485)645583..645801+219WP_003785635.1TraR/DksA C4-type zinc finger protein-
LVJ79_RS03490 (LVJ79_03490)645788..646219+432WP_003785636.1phage tail protein-
LVJ79_RS03495 (LVJ79_03495)646223..646957+735WP_003785637.1phage virion morphogenesis protein-
LVJ79_RS03500 (LVJ79_03500)647148..647432+285WP_003785638.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
LVJ79_RS03505 (LVJ79_03505)647429..647698+270WP_003785639.1type II toxin-antitoxin system YafQ family toxinToxin
LVJ79_RS03510 (LVJ79_03510)647857..648465+609WP_003785640.1phage baseplate assembly protein V-
LVJ79_RS03515 (LVJ79_03515)648462..648797+336WP_003785641.1GPW/gp25 family protein-
LVJ79_RS03520 (LVJ79_03520)648794..649690+897WP_003785643.1baseplate J/gp47 family protein-
LVJ79_RS03525 (LVJ79_03525)649687..650268+582WP_003785645.1phage tail protein I-
LVJ79_RS03530 (LVJ79_03530)650286..651686+1401WP_111694425.1phage tail protein-
LVJ79_RS03535 (LVJ79_03535)651699..651908+210WP_032133698.1hypothetical protein-
LVJ79_RS03540 (LVJ79_03540)651853..652209+357WP_003789002.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--637503..66726329760


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-77)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10329.98 Da        Isoelectric Point: 7.2429

>T233466 WP_003785639.1 NZ_CP091518:647429-647698 [Kingella kingae]
MSREIIFQGQFKRDVKKQFLELATVEWAEVLTCLVNDLPLAEKYRDHALVNDKNGYRDCHIKPDLVLIYGRKENALILVR
LGSHSEIFG

Download         Length: 270 bp

>T233466 NZ_HG941718:325684-326604 [Escherichia coli O25b:H4-ST131]
ATGGATCTGCGTGATAGCTATGCCAGGCAGGTTAAACTGTTGATGGCCGCTCTGCCGCATGTGGCGAAGGAATCCTGTTT
CGCGTTGAAAGGCGGCACAGCAATCAATTTATTTGTGCAGGATTTCCCCCGTCTATCGGTGGATATCGATCTGGCGTATA
AGAGCTTTGCGGATCGCGATACCGATCTGGCGGCGATCAACGACGCTTTGAAGAGAATTACTGCATCGCTGAACGGCAGA
CCGGGGATCACCGCGATTCGGCAGGAAAATAAAGCGGATGAAAAGCGCATCATTGTGAATACCGCTGATGCAAAGATTAA
GATCGAGGTTAGCCCGGTCTGGCGCGGGCTGTTGTTGCCTCCGGCAGAAATGCCTGTGTGCGAACGTGTGGAAATGGAGT
ATGGCTTCACCACCATGAGTGTCGTCTCGCTGGCGGATCTTTATGGCGGTAAAATATGTGCTGCGCTTGATCGTCAGCAT
CCGCGCGATCTGTTTGATGTGTTGAATATGCTGGGGAGACCGGGCCTGACGCGCGAAATTTTTGACGGTTTTCTTTGTTA
TCTGGCAGGCCATCCCCGTCCCATTGCCGAGTTGCTGGCTTCAAACTGGGATACAGATCGGATTGCCACGTTATACGCTC
AGGAATTTTCGGGGATGACTCAGCAGGAAACGTCGCTGGAATCGCTTCTGTCAGTAACGACTTTGCTGCCGCAGGCGTTG
AAGTCACATTTTACGGATCTGGATCGCGAGTTCTTGCTCAGTTTTAAGCAAAACAGCCCTGACTGGTCGCGGTATCGCTA
TCCTGAAATTCAGCATCTTCCGGCTATTCGCTGGAAGCAACGCAATCTGGCGATGCTTAAAGATAAAAATCCGGCGAAGT
ATGTGGCGGCGGTGAATAAGCTAGAGAGGGTGCTGGAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10648.21 Da        Isoelectric Point: 7.0134

>AT233466 WP_003785638.1 NZ_CP091518:647148-647432 [Kingella kingae]
MSAINFNIRMDKSLKERAFPVIESYGLTPAQAVKLFFNQIATTQTIPISFEHNVNRIPNAITRKAIEDAESEFETAKRYK
TVEEAIAAMQELAK

Download         Length: 285 bp

>AT233466 NZ_HG941718:324915-325697 [Escherichia coli O25b:H4-ST131]
TTGCCAAACTATCTAAACTGGTTGATGCAAAACACGCTACCCGGTCAGGTGCTGCTCCAGTCATGGCTTACCCGCAATGG
CGTAGATCGTAAGCTTTCTTATCTCTATGTTCAGAATGGCTGGCTCAGGCGCATCGCTCACGGTGTGTACTGCCGGACGG
GCCGTGAGCCGGATTGGGTAGACGCGGTTTACTGCCTTCAAACACAGTGGGAAAAGCCTGTTCGGGTGGCGGGGCTAACC
AGCCTTGCGCTTCAGGGCCATGCGCACTATACCGAACCGGGTAAGCCGCAGGTCTGGCTCGCGCTTCCGGCTTACGTCAA
ACTGCCGGGATGGTTTGCTGCCTTCGAACAATCAGCAACATTTATCACGCTGTATACATCGGGCCTTACCGTTGATGTCT
CGTCATTTACTACGGAACTGAAAATTGGCGACCGGCAGTTAGCAGGCAGTGCACCGGAACTGGCCGCGTATGAGATCGCC
TGCGGCGTTCCTTCGTTGATCTCGTTCGAACATGCCGATGCTCTGTTTCAGGGGGGGAATCTTCTCAGCCCACGCAAATT
GCAGGCACTGCTTCGCGCCAGTCATTCGATTAAAACCAACCGGGTGATGCTTTACCTTGCCCGGCGTAATGGACACCCTT
ATTTTCAGTATCTTGATCAAAGCGGTATAGAAACAGGTACGGGAAAGCGGCAAATCATACCTGGTGGCTGGCTGGAGCCG
GATTATCAAATTACTGTTCCCCGCACATTTAAACCGGAAGGAGTCGAAGATGGATCTGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBF5S5C3

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBF5S5C2

References