Detailed information of TA system TA233453

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 2127056..2127581
• Replicon: chromosome
• Accession: NZ_CP091508
• Organism: Uruburuella testudinis strain CCUG 63373m

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LVJ83_RS09805
• Protein ID: WP_244784317.1
• Coordinates: 2127056..2127349 (-)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LVJ83_RS09810
• Protein ID: WP_244784318.1
• Coordinates: 2127339..2127581 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LVJ83_RS09780 (LVJ83_09780)	2123557..2124306	+	750	WP_244784313.1	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	-
LVJ83_RS09785 (LVJ83_09785)	2124497..2125273	+	777	WP_244784314.1	glycosyltransferase family 2 protein	-
LVJ83_RS09790 (LVJ83_09790)	2125364..2125864	-	501	WP_244784315.1	DUF1841 family protein	-
LVJ83_RS09800 (LVJ83_09800)	2126721..2127005	-	285	WP_244784316.1	hypothetical protein	-
LVJ83_RS09805 (LVJ83_09805)	2127056..2127349	-	294	WP_244784317.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LVJ83_RS09810 (LVJ83_09810)	2127339..2127581	-	243	WP_244784318.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
LVJ83_RS09815 (LVJ83_09815)	2127691..2132193	-	4503	WP_244784319.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-72)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 11165.00 Da
• Isoelectric Point: 10.7430

>T233453 WP_244784317.1 NZ_CP091508:c2127349-2127056 [Uruburuella testudinis]
MTYELAFLPSARREWDKLDNSIKTLFKRRLAERLENPHMPSAALHGMRNAYKIKLRQAGYRLVYTVDDGLITVTVVAVGR
RDKSTVYVQALARAKDK

Nucleotide

• Length: 294 bp

>T233453 NZ_HG938356:535461-535790 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
ATGGAGCGTGGCGACATCTGGCATGTGGATCTGGAGCCAATAAAGGGACGCGAACAGGCGGGCTCTCGCTACGCGTTGAT
CGTCACTCAGAAGAGCTTCAACAATGTCGGAACGCCCGTCATCGTGCCGATCACCACCGGTGGGCAGTTTGCCCGTTTTC
AAGGGTTTGCGGTTTCCTTGTCTGGTGCTGGCACCCGGAGTTCGGGCGTTGTCCTGTGCAACCAGTTGCGGGCGGTCGAT
CTGAAAGCTCGTGGCGCCCGCTTTGTGGAGCGGGTTCCCGACTTCATCATGGATGAAGTTTTGGCTCGGATCAGTACGTT
TTTCGAATAG

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8903.06 Da
• Isoelectric Point: 4.0414

>AT233453 WP_244784318.1 NZ_CP091508:c2127581-2127339 [Uruburuella testudinis]
MEAVLADYAVSVTELKRNYAAIMAQADGAVAVLNHNKPEAYLISAERYQALLEYMEDLEDVKLALERSDEQAVKVSLDDL

Nucleotide

• Length: 243 bp

>AT233453 NZ_HG938356:535204-535461 [Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI]
ATGGCATCCTCGACTTTGCGAAACGTTGGCGGCTCGGTGATGATGGCGATCCCGAAGCCGGTGCTGGAAGAGCTCGGCCT
ATCGGCCAATACGAAGCTGGAGGTTTCGGCCGAAGGCGGACGGATCGTGGCATCGCCGCAAACCCGGCCGAAATACACTC
TGGATGAGCTTCTCGCCCAGTGCGATCTGGATGCGCCATTTACGGAGGAGGATTTGGAATGGCTTAACGATCCGCCCGTT
GGTCGGGAGATCATCTGA