Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2216743..2216911 Replicon chromosome
Accession NZ_CP091470
Organism Klebsiella michiganensis strain KO_408

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2216801..2216904 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2216743..2216911 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3249_RS10560 (L3249_10580) 2211870..2213930 + 2061 WP_014229840.1 oligopeptidase B -
L3249_RS10565 (L3249_10585) 2213937..2214596 - 660 WP_014229839.1 exodeoxyribonuclease X -
L3249_RS10570 (L3249_10590) 2214675..2214905 - 231 WP_004103351.1 DNA polymerase III subunit theta -
L3249_RS10575 (L3249_10595) 2215041..2215415 + 375 WP_014229838.1 CopC domain-containing protein YobA -
L3249_RS10580 (L3249_10600) 2215420..2216289 + 870 WP_014229837.1 copper homeostasis membrane protein CopD -
L3249_RS10585 (L3249_10605) 2216306..2216644 + 339 WP_004103344.1 YebY family protein -
- 2216743..2216911 - 169 - - Antitoxin
- 2216801..2216904 + 104 - - Toxin
L3249_RS10590 (L3249_10610) 2217029..2217988 - 960 WP_088168007.1 spore coat protein U domain-containing protein -
L3249_RS10595 (L3249_10615) 2218003..2220333 - 2331 WP_195377939.1 fimbria/pilus outer membrane usher protein -
L3249_RS10600 (L3249_10620) 2220336..2221100 - 765 WP_032694916.1 fimbria/pilus periplasmic chaperone -
L3249_RS10605 (L3249_10625) 2221119..2221637 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T233362 NZ_CP091470:2216801-2216904 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT233362 NZ_CP091470:c2216911-2216743 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References