Detailed information of TA system TA233356

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 1273686..1274339
• Replicon: chromosome
• Accession: NZ_CP091465
• Organism: Acinetobacter baumannii strain NCCP 16007

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: L3080_RS05860
• Protein ID: WP_000607077.1
• Coordinates: 1273686..1274075 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: L3080_RS05865
• Protein ID: WP_001288210.1
• Coordinates: 1274082..1274339 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L3080_RS05845	1268804..1270999	-	2196	WP_001158906.1	TRAP transporter large permease subunit	-
L3080_RS05850	1271187..1271753	-	567	WP_000651538.1	rhombosortase	-
L3080_RS05855	1271831..1272916	-	1086	WP_000049106.1	hypothetical protein	-
L3080_RS05860	1273686..1274075	-	390	WP_000607077.1	membrane protein	Toxin
L3080_RS05865	1274082..1274339	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
L3080_RS05870	1274527..1275699	+	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
L3080_RS05875	1275748..1277238	-	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
L3080_RS05880	1277420..1277797	-	378	WP_001216380.1	50S ribosomal protein L17	-
L3080_RS05885	1277816..1278823	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T233356 WP_000607077.1 NZ_CP091465:c1274075-1273686 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T233356 NZ_HG813240:1689837-1690154 [Mycobacterium tuberculosis 49-02]
GTGAACGCGCCGTTGCGTGGTCAGGTCTATCGATGCGACCTCGGATACGGGGCCAAACCGTGGCTCATCGTCTCCAACAA
CGCCCGCAACCGTCACACCGCCGACGTGGTGGCTGTGCGCCTGACAACAACGCGGAGAACCATACCGACCTGGGTCGCCA
TGGGCCCCAGCGATCCATTGACCGGATACGTCAACGCGGACAACATCGAGACCCTCGGCAAAGACGAGCTCGGTGACTAC
CTCGGTGAGGTCACGCCGGCGACGATGAACAAAATCAACACGGCGCTCGCGACCGCGCTGGGGCTACCGTGGCCATGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT233356 WP_001288210.1 NZ_CP091465:c1274339-1274082 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT233356 NZ_HG813240:1689538-1689840 [Mycobacterium tuberculosis 49-02]
GTGCCGTTTCTGGTTGCATTATCCGGTATCATCTCGGGCGTGCGTGATCATTCGATGACCGTGCGGCTCGACCAGCAAAC
TCGCCAGCGCCTGCAAGACATTGTGAAAGGCGGATACCGGAGCGCTAATGCGGCGATCGTCGACGCCATCAACAAGCGCT
GGGAGGCGCTACACGATGAGCAACTCGACGCCGCCTACGCGGCCGCGATCCATGACAATCCGGCGTACCCGTACGAGTCT
GAGGCCGAACGGAGCGCCGCGCGGGCCCGGCGCAACGCCAGGCAGCAGCGCTCGGCACAGTGA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7