Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1534793..1535380 Replicon chromosome
Accession NZ_CP091456
Organism Avibacterium sp. 20-132

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L4F93_RS07310 Protein ID WP_250349674.1
Coordinates 1535084..1535380 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L4F93_RS07305 Protein ID WP_250351659.1
Coordinates 1534793..1535083 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L4F93_RS07285 (L4F93_07285) 1531181..1531369 - 189 WP_250349671.1 hypothetical protein -
L4F93_RS07290 (L4F93_07290) 1531462..1531893 + 432 Protein_1400 phage minor head protein -
L4F93_RS07295 (L4F93_07295) 1532248..1533435 + 1188 WP_250349672.1 porin -
L4F93_RS07300 (L4F93_07300) 1533870..1534595 - 726 WP_250349673.1 carboxy-S-adenosyl-L-methionine synthase CmoA -
L4F93_RS07305 (L4F93_07305) 1534793..1535083 + 291 WP_250351659.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
L4F93_RS07310 (L4F93_07310) 1535084..1535380 + 297 WP_250349674.1 type II toxin-antitoxin system YafQ family toxin Toxin
L4F93_RS07315 (L4F93_07315) 1535465..1537234 + 1770 WP_250349675.1 aspartate--tRNA ligase -
L4F93_RS07320 (L4F93_07320) 1537277..1537720 + 444 WP_250349676.1 dihydroneopterin triphosphate diphosphatase -
L4F93_RS07325 (L4F93_07325) 1538094..1538834 + 741 WP_250349677.1 YebC/PmpR family DNA-binding transcriptional regulator -
L4F93_RS07330 (L4F93_07330) 1538912..1539472 + 561 WP_250349678.1 crossover junction endodeoxyribonuclease RuvC -
L4F93_RS07335 (L4F93_07335) 1539559..1540173 + 615 WP_250349679.1 Holliday junction branch migration protein RuvA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(9-97)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-74)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11573.68 Da        Isoelectric Point: 7.9396

>T233349 WP_250349674.1 NZ_CP091456:1535084-1535380 [Avibacterium sp. 20-132]
MSQPLPINEIEMAKEFKRDLVQLAKKMPHLFVHPRYLEVMHYLTNGITLPAEYKNHPLKDNLKGYMDCHILNDLVLIYKI
EQQCLKLVRLNTHSEVFA

Download         Length: 297 bp

>T233349 NZ_HG813240:1013314-1013748 [Mycobacterium tuberculosis 49-02]
ATGGCGAAACTGTCCGGATCCATCGACGTACCGCTGCCACCGGAGGAAGCCTGGATGCACGCCTCCGATCTGACTCGTTA
CCGAGAGTGGCTGACCATCCACAAGGTATGGCGCAGCAAGTTGCCCGAAGTGCTCGAGAAGGGCACGGTCGTCGAGTCGT
ATGTCGAGGTCAAGGGCATGCCCAACCGGATCAAGTGGACGATCGTGCGGTACAAACCCCCGGAGGGCATGACGCTCAAC
GGCGACGGTGTGGGTGGTGTCAAAGTCAAGCTGATCGCTAAGGTAGCGCCGAAAGAGCACGGCTCCGTCGTCAGCTTCGA
TGTGCACCTCGGCGGCCCGGCCCTGCTCGGGCCGATCGGCATGATCGTCGCCGCTGCATTGCGAGCCGACATCCGCGAAT
CGCTGCAGAACTTCGTCACGGTGTTTGCCGGCTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10731.31 Da        Isoelectric Point: 5.0508

>AT233349 WP_250351659.1 NZ_CP091456:1534793-1535083 [Avibacterium sp. 20-132]
MTNNNAVVNFRLPQHLKTEAFEVIAQYGLTPSQVFNMFLTEIVATKAIPLSLNYLQPNTKTLMAMDEIENGKAERFSLDA
NTDLASLLKQKAEGKE

Download         Length: 291 bp

>AT233349 NZ_HG813240:1013129-1013308 [Mycobacterium tuberculosis 49-02]
ATGGGAATCCTGGACAAGGTAAAGAACCTGCTGTCGCAGAACGCCGACAAGGTCGAGACGGTGATCAACAAAGCGGGCGA
ATTCGTCGACGAGCAGACGCAAGGCAATTATTCTGACGCCATCCACAAGCTGCATGACGCGGCCAGCAACGTCGTCGGCA
TGAGCGACCAGCAGAGCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References