Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/- |
Location | 2323699..2324352 | Replicon | chromosome |
Accession | NZ_CP091373 | ||
Organism | Acinetobacter baumannii strain AB21-VUB |
Toxin (Protein)
Gene name | cptA | Uniprot ID | - |
Locus tag | L2Z46_RS11190 | Protein ID | WP_000607070.1 |
Coordinates | 2323699..2324088 (-) | Length | 130 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | V5V966 |
Locus tag | L2Z46_RS11195 | Protein ID | WP_001288210.1 |
Coordinates | 2324095..2324352 (-) | Length | 86 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
L2Z46_RS11175 (L2Z46_11175) | 2318817..2321012 | - | 2196 | WP_001158905.1 | TRAP transporter large permease subunit | - |
L2Z46_RS11180 (L2Z46_11180) | 2321200..2321766 | - | 567 | WP_000651536.1 | rhombosortase | - |
L2Z46_RS11185 (L2Z46_11185) | 2321844..2322929 | - | 1086 | WP_000049107.1 | hypothetical protein | - |
L2Z46_RS11190 (L2Z46_11190) | 2323699..2324088 | - | 390 | WP_000607070.1 | hypothetical protein | Toxin |
L2Z46_RS11195 (L2Z46_11195) | 2324095..2324352 | - | 258 | WP_001288210.1 | succinate dehydrogenase assembly factor 2 | Antitoxin |
L2Z46_RS11200 (L2Z46_11200) | 2324540..2325712 | + | 1173 | WP_001190546.1 | acyl-CoA dehydrogenase family protein | - |
L2Z46_RS11205 (L2Z46_11205) | 2325762..2327252 | - | 1491 | WP_000415133.1 | NAD(P)/FAD-dependent oxidoreductase | - |
L2Z46_RS11210 (L2Z46_11210) | 2327433..2327810 | - | 378 | WP_001216380.1 | 50S ribosomal protein L17 | - |
L2Z46_RS11215 (L2Z46_11215) | 2327829..2328836 | - | 1008 | WP_000198631.1 | DNA-directed RNA polymerase subunit alpha | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 130 a.a. Molecular weight: 15708.02 Da Isoelectric Point: 10.3599
>T233260 WP_000607070.1 NZ_CP091373:c2324088-2323699 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEDHKTLTSIIWFDQMSLAEWKKLKTLEKLY
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEDHKTLTSIIWFDQMSLAEWKKLKTLEKLY
Download Length: 390 bp
>T233260 NZ_HF572917:c3297531-3297196 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTATACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTATACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG
Antitoxin
Download Length: 86 a.a. Molecular weight: 10318.77 Da Isoelectric Point: 4.6150
>AT233260 WP_001288210.1 NZ_CP091373:c2324352-2324095 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG
Download Length: 258 bp
>AT233260 NZ_HF572917:c3297779-3297531 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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