Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 1115098..1115751 Replicon chromosome
Accession NZ_CP091368
Organism Acinetobacter baumannii strain AB167-VUB

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag L2Z06_RS05170 Protein ID WP_000607077.1
Coordinates 1115098..1115487 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag L2Z06_RS05175 Protein ID WP_001288210.1
Coordinates 1115494..1115751 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2Z06_RS05155 (L2Z06_05155) 1110216..1112411 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
L2Z06_RS05160 (L2Z06_05160) 1112599..1113165 - 567 WP_000651538.1 rhombosortase -
L2Z06_RS05165 (L2Z06_05165) 1113243..1114328 - 1086 WP_000049106.1 hypothetical protein -
L2Z06_RS05170 (L2Z06_05170) 1115098..1115487 - 390 WP_000607077.1 membrane protein Toxin
L2Z06_RS05175 (L2Z06_05175) 1115494..1115751 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
L2Z06_RS05180 (L2Z06_05180) 1115939..1117111 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
L2Z06_RS05185 (L2Z06_05185) 1117160..1118650 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
L2Z06_RS05190 (L2Z06_05190) 1118832..1119209 - 378 WP_001216380.1 50S ribosomal protein L17 -
L2Z06_RS05195 (L2Z06_05195) 1119228..1120235 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T233252 WP_000607077.1 NZ_CP091368:c1115487-1115098 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T233252 NZ_HF572917:c1466865-1466758 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT233252 WP_001288210.1 NZ_CP091368:c1115751-1115494 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp

>AT233252 NZ_HF572917:1466913-1466979 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References