Detailed information of TA system TA233247

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3326199..3326852
• Replicon: chromosome
• Accession: NZ_CP091365
• Organism: Acinetobacter baumannii strain AB172-VUB

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: L2Z09_RS15900
• Protein ID: WP_000607077.1
• Coordinates: 3326199..3326588 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: L2Z09_RS15905
• Protein ID: WP_001288210.1
• Coordinates: 3326595..3326852 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2Z09_RS15885 (L2Z09_15880)	3321317..3323512	-	2196	WP_001158909.1	TRAP transporter large permease subunit	-
L2Z09_RS15890 (L2Z09_15885)	3323700..3324266	-	567	WP_000651538.1	rhombosortase	-
L2Z09_RS15895 (L2Z09_15890)	3324344..3325429	-	1086	WP_000049106.1	hypothetical protein	-
L2Z09_RS15900 (L2Z09_15895)	3326199..3326588	-	390	WP_000607077.1	membrane protein	Toxin
L2Z09_RS15905 (L2Z09_15900)	3326595..3326852	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
L2Z09_RS15910 (L2Z09_15905)	3327040..3328212	+	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
L2Z09_RS15915 (L2Z09_15910)	3328261..3329751	-	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
L2Z09_RS15920 (L2Z09_15915)	3329930..3330307	-	378	WP_001216380.1	50S ribosomal protein L17	-
L2Z09_RS15925 (L2Z09_15920)	3330326..3331333	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T233247 WP_000607077.1 NZ_CP091365:c3326588-3326199 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T233247 NZ_HF571988:c4860255-4859836 [Yersinia enterocolitica (type O:5) str. YE53/03]
ATGATCAAAAAATTATATATGCTTGATACGAATATTTGTTCTTTTATTATGCGAGAACGACCAGCAGAATTAATTATAAA
ATTACAACAGTGTATTGAGCATCAGAATAAAATAGTTGTTTCAGCAATTACATACTCAGAAATGCGGTTCGGCGCTATAG
GTAAGAAAGCATCTCCAAAGCATAATTATTTAGTTGATGAATTTGTAAAAAGGTTAGATGCTATTTTACCGTGGGATGTC
GCAGCTGTTGATGCCACGACTAATATTAAAGTTGAGCTGGCAAAGCAGGGGACACCAATTGGCGGAAATGATGCCGCAAT
AGCCGGGCATGCAGTTTCTGCTGGAGCAATATTAGTAACTAATAATATTAGAGAGTTTGAACGAGTTAAAAAACTACGAA
TTGAAGATTGGACTCAATAG

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT233247 WP_001288210.1 NZ_CP091365:c3326852-3326595 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT233247 NZ_HF571988:c4860479-4860252 [Yersinia enterocolitica (type O:5) str. YE53/03]
ATGAGAACGGTATCTATTTTCAAAAATGGGCAGAATCGAGCAATTCGTTTGCCAAAAGATATGGATTTTGATGGCGTGAC
CGAGCTGGAAATACTCAGGGATGGTGATAGTATTATTCTACGACCCATACGCCCGACATGGGTATCATTCATGGATGAAG
ATAAGGCAGATGATGATTTTCTTGCCGAAAGACAGGATGTTATCGAAGAAGGACGCTTCGAGTTATGA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7