233242

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 1721820..1722473 Replicon chromosome
Accession NZ_CP091362
Organism Acinetobacter baumannii strain AB176-VUB

Toxin (Protein)


Gene name cptA Uniprot ID B0V6V2
Locus tag L2Z12_RS08115 Protein ID WP_000931890.1
Coordinates 1721820..1722209 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag L2Z12_RS08120 Protein ID WP_001288210.1
Coordinates 1722216..1722473 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2Z12_RS08100 (L2Z12_08090) 1716939..1719134 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
L2Z12_RS08105 (L2Z12_08095) 1719322..1719888 - 567 WP_000651536.1 rhombosortase -
L2Z12_RS08110 (L2Z12_08100) 1719966..1721051 - 1086 WP_000049106.1 hypothetical protein -
L2Z12_RS08115 (L2Z12_08105) 1721820..1722209 - 390 WP_000931890.1 membrane protein Toxin
L2Z12_RS08120 (L2Z12_08110) 1722216..1722473 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
L2Z12_RS08125 (L2Z12_08115) 1722661..1723833 + 1173 WP_001190546.1 acyl-CoA dehydrogenase family protein -
L2Z12_RS08130 (L2Z12_08120) 1723883..1725373 - 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
L2Z12_RS08135 (L2Z12_08125) 1725552..1725929 - 378 WP_001216380.1 50S ribosomal protein L17 -
L2Z12_RS08140 (L2Z12_08130) 1725948..1726955 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15649.98 Da        Isoelectric Point: 10.4623

>T233242 WP_000931890.1 NZ_CP091362:c1722209-1721820 [Acinetobacter baumannii]
MLNHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T233242 NZ_HF571988:2527901-2528359 [Yersinia enterocolitica (type O:5) str. YE53/03]
ATGATGCTCTACCGCATTGTGATGCGCCGCTATCTTGCCTCAACCTGGACCGGCTATGGTGCCGAAATCTATGGTGGCCG
CTGGAATCATAAGGGGCACGCCGCCATCTACTTAGCCAGCAGTGTATCACTGGCGATGTTGGAGACGTTGGTACATATTC
AGGACAGCTCAACACTAAGTGAGTTCGAGTTATTCCAAATTGAAATCGAAGATAGCAACATTATGCTGCTTCAGCCGCAG
GATTGGCCCACGGACTGGCGCAGCGACCCCGCACCTGCGACCACAATGGATATCGGCACTGAATGGCTGGAGTCAGAATC
ATCACTTGGATTACTGGTTCCATCCACTCTGGTGCCGACAGAAAACAATCTACTGCTCAATCCTCGGCACAAAAGCTTTC
AAGCCTGCCTAAGCAGTGTTCAACCGCTCTCTTTTGCCTTTGACCCACGGCTGAAATAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT233242 WP_001288210.1 NZ_CP091362:c1722473-1722216 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp

>AT233242 NZ_HF571988:2527399-2527845 [Yersinia enterocolitica (type O:5) str. YE53/03]
ATGAGAGCGTATCACCCCACTCCAGCGACCAAAACAGGGGCGCTATGGCGAGAGATTGGTTTGCCCGCGAGCCGCGGTAC
TGTATTGGTCGATAGCATCAAAATGGGTTTTTCTGTTGATGTCATTGACAGCATCCATCTATGGGCATCAATCCCCAAAG
CTGAAATCTTGCGTGCGACCGGCATTCCCAGCCGTAGCTTGACTCGCAGGCGCACACATGATGGCCGTTTCACTCCTGAA
GAGAGTGAGCGAATTGCGCGTTTTGTTCGGGTTATGGACGCCGCAGTTGATCTATTTGGCGGAGATAAAGGCAAAGCTAT
CACTTGGATGTCGACCCCGATCAAAGGCCTGGGTCACCGTAGTCCGGATTCCTTACTGGAAACCGAAACCGGTGCATTGG
AAGTCTGTGATTTGATTGGACGCCTGGAGCACGGCGTATTTTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0J1A4U0

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References