Detailed information of TA system TA233240

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 1747787..1748440
• Replicon: chromosome
• Accession: NZ_CP091361
• Organism: Acinetobacter baumannii strain AB177-VUB

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: A0A9E9PBS3
• Locus tag: L2Z13_RS08435
• Protein ID: WP_002096593.1
• Coordinates: 1747787..1748176 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A2G8V6F0
• Locus tag: L2Z13_RS08440
• Protein ID: WP_029424136.1
• Coordinates: 1748183..1748440 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2Z13_RS08420 (L2Z13_08420)	1742905..1745100	-	2196	WP_001158905.1	TRAP transporter large permease subunit	-
L2Z13_RS08425 (L2Z13_08425)	1745288..1745854	-	567	WP_000651536.1	rhombosortase	-
L2Z13_RS08430 (L2Z13_08430)	1745932..1747017	-	1086	WP_000049106.1	hypothetical protein	-
L2Z13_RS08435 (L2Z13_08435)	1747787..1748176	-	390	WP_002096593.1	hypothetical protein	Toxin
L2Z13_RS08440 (L2Z13_08440)	1748183..1748440	-	258	WP_029424136.1	succinate dehydrogenase assembly factor 2	Antitoxin
L2Z13_RS08445 (L2Z13_08445)	1748628..1749800	+	1173	WP_001190550.1	acyl-CoA dehydrogenase family protein	-
L2Z13_RS08450 (L2Z13_08450)	1749849..1751339	-	1491	WP_000415132.1	NAD(P)/FAD-dependent oxidoreductase	-
L2Z13_RS08455 (L2Z13_08455)	1751520..1751897	-	378	WP_001216380.1	50S ribosomal protein L17	-
L2Z13_RS08460 (L2Z13_08460)	1751916..1752923	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-80)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15677.99 Da
• Isoelectric Point: 10.3890

>T233240 WP_002096593.1 NZ_CP091361:c1748176-1747787 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLVEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T233240 NZ_HF571988:1162988-1163965 [Yersinia enterocolitica (type O:5) str. YE53/03]
ATGGATAAATTATCAATGATTTTTGCAGATGTTGCCGATGCCTTGGGGATCGGTGCAACATCTATCGTTGAAAAAGATTA
TTATGTTATTGAGTTACTTCGCCTATTACAGCCTTTGATATTTGAGACACATCAACTTGTGTTTGCTGGAGGAACATCTC
TGGCGAAATCGGGTATTAAATTAAATCGGATGTCTGAGGATGTAGATATAAAACTTATCCCCAATCCGGATTTTCTTGAT
GATACCCATTTCTCGCGTTCACAACGTAAAAATACGAGAAAGGAAATTATCGAAAAAATATCAGATATTATTATTGCATC
AGAGCTATTTAAGTTCGATAAGAGCTATCCAAGAATAGCTCGGGATGAATATCGATATAATGATATTCAAATCCAATACC
CTCAAGAGTTTACTCAAGTCCCTTGTCTTAGACCTTTCATCAAGCTGGAATTAATGGAATCAGATTTGTTAGAACCGGCT
GAGTTGCGAAATATTAGTTCTTTTGTCTACGAGTTAGCAGGAAAAGGGAGCGAAATATCTGCATTTCCTTGTACAACAAT
TATCAGCACTCAAGCTGAAAAGATAGTTGCCATGATGAGGCGTACGGCTGCATTTATGAGAAATGTAGACCGCAAAGATG
ACGAATCGTTGGTTCGCCATATTTACGATAATTATCGCATTGTTGATGCCTTGGGTTTAAATATTTGTCAGCTATCAGTT
TTTGTGCAACAGACGATTCAACTAGATATTGAGCGTTATGGATGCCAGCATCCGCAATTGAAAGCGAATGCTATAGATGA
ACTTAAAACGGGATTAGACGAGATTGGTAGTAACCCCTATTTTAAAGAGCGCTATGGGCAGTTTGTGGTTCCAATGGTAT
TTGAGAATAGCAGGGTTGAATGGGAAGAGGTTTATCACTGTTTTCGTCAGACGGCATTGGAAACTTTGAAATGTTTAGAT
GGCTCATTAACTAAGTAG

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10360.85 Da
• Isoelectric Point: 4.4909

>AT233240 WP_029424136.1 NZ_CP091361:c1748440-1748183 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADLAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
YYVHG

Nucleotide

• Length: 258 bp

>AT233240 NZ_HF571988:1162600-1162995 [Yersinia enterocolitica (type O:5) str. YE53/03]
ATGACTATCAAAGAACGTATTCAAACGAGATTAAAACGTTCTAAACGTTACGTGTTTACTCGTGATGATTTCAAAGATAT
TGCTGATTACGATCAGATTGGTCGCGTGTTGCGTAATCTAGTGAAAGAAGGATTATTGCTTAGGGTGGGGTATGGACTGT
ACACCAAAGCGCGTAAGAACTCGATCACTGGTAAGATCATGCCTGCCTCTCCTGGCGGTTCTGACGCAGTTATTCTTGAG
TCACTTGACCGTTTGAATGTTCATTACACATTGGATGCCAGCACGACTAAGTATATAAAAGGTGAAACAACGCAAGTACC
TGCTTACACTCAAGTCAAGACGTCGCCTCGCTTCAAACGTGCATTGTCCGTTGGGAATAGCAGATTGAATGGATAA

Structures

Antitoxin

• AlphaFold DB: A0A2G8V6F0