Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 531999..532652 Replicon chromosome
Accession NZ_CP091358
Organism Acinetobacter baumannii strain AB181-VUB

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag L2Z17_RS02665 Protein ID WP_000607077.1
Coordinates 532263..532652 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag L2Z17_RS02660 Protein ID WP_001288210.1
Coordinates 531999..532256 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2Z17_RS02640 (L2Z17_02640) 527515..528522 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
L2Z17_RS02645 (L2Z17_02645) 528541..528918 + 378 WP_001216380.1 50S ribosomal protein L17 -
L2Z17_RS02650 (L2Z17_02650) 529100..530590 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
L2Z17_RS02655 (L2Z17_02655) 530639..531811 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
L2Z17_RS02660 (L2Z17_02660) 531999..532256 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
L2Z17_RS02665 (L2Z17_02665) 532263..532652 + 390 WP_000607077.1 membrane protein Toxin
L2Z17_RS02670 (L2Z17_02670) 533422..534507 + 1086 WP_000049106.1 hypothetical protein -
L2Z17_RS02675 (L2Z17_02675) 534585..535151 + 567 WP_000651538.1 rhombosortase -
L2Z17_RS02680 (L2Z17_02680) 535339..537534 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T233229 WP_000607077.1 NZ_CP091358:532263-532652 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T233229 NZ_FO834906:c3599222-3599120 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT233229 WP_001288210.1 NZ_CP091358:531999-532256 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp

>AT233229 NZ_FO834906:3599113-3599258 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References