Detailed information of TA system TA233213

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 1684304..1684957
• Replicon: chromosome
• Accession: NZ_CP091350
• Organism: Acinetobacter baumannii strain AB212-VUB

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: L2Z25_RS08150
• Protein ID: WP_000607077.1
• Coordinates: 1684304..1684693 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: L2Z25_RS08155
• Protein ID: WP_001288210.1
• Coordinates: 1684700..1684957 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2Z25_RS08135 (L2Z25_08135)	1679422..1681617	-	2196	WP_202739532.1	TRAP transporter large permease subunit	-
L2Z25_RS08140 (L2Z25_08140)	1681805..1682371	-	567	WP_000651538.1	rhombosortase	-
L2Z25_RS08145 (L2Z25_08145)	1682449..1683534	-	1086	WP_000049106.1	hypothetical protein	-
L2Z25_RS08150 (L2Z25_08150)	1684304..1684693	-	390	WP_000607077.1	membrane protein	Toxin
L2Z25_RS08155 (L2Z25_08155)	1684700..1684957	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
L2Z25_RS08160 (L2Z25_08160)	1685145..1686317	+	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
L2Z25_RS08165 (L2Z25_08165)	1686366..1687856	-	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
L2Z25_RS08170 (L2Z25_08170)	1688038..1688415	-	378	WP_001216380.1	50S ribosomal protein L17	-
L2Z25_RS08175 (L2Z25_08175)	1688434..1689441	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T233213 WP_000607077.1 NZ_CP091350:c1684693-1684304 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T233213 NZ_FO818637:c3913633-3912716 [Xenorhabdus bovienii]
ATGGATAAATATTCGCCGTACTACCGACAAGTTGCATTACTCATAAGCGCACTCCTTGTGGTGGCATCGGAGCGCTGTTT
TGCGCTAAAGGGTGGGACGGCAATTAATCTGTTTGTGCGTGATTTTCCTCGTTTGTCGGTTGACATTGATTTGGTCTATG
TACCACTGGAAAGCAGGGACGTAGCTTTGGCTAATGTTCGGGCTGCTTTAACCCGTATCACTGGGTTGCTCCAACAACAA
GTGGGTGTTTCGGCAATACTGCAAACGAATAACCATGATGAGATGCGCATTATTGTCTCTTCTCAAGAGGCACAAATAAA
GATTGAGGTTTCACCCGTGGCGCGTGGAACGCTATATCCTTCCCAGGATCTTGATGTTGCTGAGGCGGTAGAAGACGAGT
TTGGTTTTGCCACTATTCAGGTTGTCTCAATGGCTGATCTTTATGGTGGCAAACTGTGTGCTGCATTAGACCGTCAGCAT
CCACGCGATCTTTATGACGTTAAAATGTTACTCGAAACGCAAGGGATAGATCGCCACATATTTAATGGATTTATCACCTA
TCTACTGAGTCATCCCCGACCGTTGTCCGAAGTATTGAATCCCCGTTGGAAAGATATCTCAGAGCTTTATGCTCATGAGT
TTAGCGGAATGACATTTGATAACGTATCGCTGGAAGAACTCAATGTTGTACCTGAATTTATGATTTCTGCCCTCAAGTCG
CAATTCACTCAGCAGGATTTTGATTTCCTAATATCCTTCAAAAGCGGTGAGCCGGATTGGCAACTTGTCCCTGAGAGCCA
AATTCAGCATTTACCCGCAGTAAAATGGAAGTTACACAACATTGGCCGTATACCTGAAGAGAAACATATTCAGGCGCTGG
AGAAACTTGAGAGAGTACTGAACGATTGGATGGGATAG

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT233213 WP_001288210.1 NZ_CP091350:c1684957-1684700 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT233213 NZ_FO818637:c3914399-3913626 [Xenorhabdus bovienii]
ATGTCATCAAAATTAAACTGGCTTTTGCAAAATACTGCGCCGGGCTCTCTGGTGTTGCAATCCTGGCTGACAAAACACGG
TATCAGTCCCTCGCTAGCGAATAAGTACATGCATAGTAACTGGTTACAAAAATTACGAACCGGGGTGTACGTGCGGGCTG
GGCGTGATCCTGAGTGGTGGGATGTGGTGTTGTGCTTGCAAAACCAGCTTGGTTTCCCAGTACATCTGGCGGGGCTTACC
AGCTTGGGATATCAGGGGCGCTCTCATTATCTTCAGTTCAAGCAACAAGCCATTTGGCTCTATGTGCAAGATAAAGCTGC
GTTGCCAAAGTGGTTCAAAGAATTCCCCAATATCGAGTGGCTTTTACTTTCTAATCAGAAGCTCGCTAAACATGATGAAA
AATACCTGACAGAGGTAGAAATCAAGGGGGAACAGCTAAGAACGAGTGTGCCTGAGTTGGCAGCTTATGAGATTGCCAAT
GCTGTACCAGGGATACTTTCGTTTGAACACGCCGCCGAACTTTTTCAAGGGCTAGTGAATCTGAGCCCCCGTAAAGTAGA
AGCGCTGTTGCAATCTAGCCGAGCGGTGCAAACTAATCGTCTTTATCTGTTTCTGGCTGATTATTATGCTCATGCATGGG
CTAAGCGTTTAGATCAAACCAACATTGATTTAGGAGCAGGGAAGCGGCAGATTGTGTCTGGTGGTAAGTTAGATAGGAAA
TACCAAATCACCGTTCCTGAAAAATTTGTGAGCCATGGGTTATTACATGGATAA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7