Detailed information of TA system TA233211

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 633171..633824
• Replicon: chromosome
• Accession: NZ_CP091349
• Organism: Acinetobacter baumannii strain AB213-VUB

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: L2Z27_RS02905
• Protein ID: WP_000607077.1
• Coordinates: 633171..633560 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: L2Z27_RS02910
• Protein ID: WP_001288210.1
• Coordinates: 633567..633824 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2Z27_RS02890 (L2Z27_02890)	628289..630484	-	2196	WP_001158906.1	TRAP transporter large permease subunit	-
L2Z27_RS02895 (L2Z27_02895)	630672..631238	-	567	WP_000651538.1	rhombosortase	-
L2Z27_RS02900 (L2Z27_02900)	631316..632401	-	1086	WP_000049106.1	hypothetical protein	-
L2Z27_RS02905 (L2Z27_02905)	633171..633560	-	390	WP_000607077.1	membrane protein	Toxin
L2Z27_RS02910 (L2Z27_02910)	633567..633824	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
L2Z27_RS02915 (L2Z27_02915)	634012..635184	+	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
L2Z27_RS02920 (L2Z27_02920)	635233..636723	-	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
L2Z27_RS02925 (L2Z27_02925)	636905..637282	-	378	WP_001216380.1	50S ribosomal protein L17	-
L2Z27_RS02930 (L2Z27_02930)	637301..638308	-	1008	WP_077123802.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T233211 WP_000607077.1 NZ_CP091349:c633560-633171 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T233211 NZ_FO818637:1751830-1752141 [Xenorhabdus bovienii]
ATGATATTCATTGAGACTCATATATTCACCGAAGACTGTAAAGAGCTGTTAAGTGATGATGAATATCGCGAGTTTCAGCA
ATATCTTGCAGACAATCCCGCTACGGGTGATGTTATCCAGCACACTGGGGGCTTACGTAAAGTTAGATGGGCATCCAGAG
GTAAAGGTAAACGTGGCGGTGTACGCGTCATTTATTATCACAAGGTCGATGTCTCACATATAAGACTGCTTCTGATTTAT
AAAAAAGGTATTAAAGATGACCTTAGCGAGTCAGAAAAGAAAGTCTTGAGAGCATTAAATGAGGGGTGGTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT233211 WP_001288210.1 NZ_CP091349:c633824-633567 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT233211 NZ_FO818637:1752144-1752434 [Xenorhabdus bovienii]
ATGGACAGTAAATTATTTTCCAGACTCACTGAAAGCATGACACAGATGAACGAAATCATGAATGGCGAACGTGCTGCTTC
TCGTGAAACAACTATTGAGGCAGTGAAAGTAAAAAACATTCGTCAGGCAACCGGATTGAGCCAGACGGGTTTTGCTAAAT
TAATCTCTGTTAATGTTGGAACCCTTCGTAATTGGGAACAGGGAAGAAGAGAGCCAACAGGCCCAGCAAAAGCATTGTTA
AAGGCAATAGAGAAAGATCCGGTTCATGTCTTAAAGGCGTTATCTATGTAG

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7