Detailed information of TA system TA233208

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 80601..81254
• Replicon: chromosome
• Accession: NZ_CP091347
• Organism: Acinetobacter baumannii strain AB216-VUB

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: L2Z29_RS00410
• Protein ID: WP_000607077.1
• Coordinates: 80601..80990 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: L2Z29_RS00415
• Protein ID: WP_001288210.1
• Coordinates: 80997..81254 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2Z29_RS00395 (L2Z29_00395)	75719..77914	-	2196	WP_001158906.1	TRAP transporter large permease subunit	-
L2Z29_RS00400 (L2Z29_00400)	78102..78668	-	567	WP_000651538.1	rhombosortase	-
L2Z29_RS00405 (L2Z29_00405)	78746..79831	-	1086	WP_000049106.1	hypothetical protein	-
L2Z29_RS00410 (L2Z29_00410)	80601..80990	-	390	WP_000607077.1	membrane protein	Toxin
L2Z29_RS00415 (L2Z29_00415)	80997..81254	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
L2Z29_RS00420 (L2Z29_00420)	81442..82614	+	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
L2Z29_RS00425 (L2Z29_00425)	82663..84153	-	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
L2Z29_RS00430 (L2Z29_00430)	84335..84712	-	378	WP_001216380.1	50S ribosomal protein L17	-
L2Z29_RS00435 (L2Z29_00435)	84731..85738	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T233208 WP_000607077.1 NZ_CP091347:c80990-80601 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T233208 NZ_FO818637:c323528-323235 [Xenorhabdus bovienii]
ATGAAATTTAATATCGACTTCGACGAACGCGCCTTGAAGGAGTGGCATAAACTGGATAAAAGTATACGGGAGCAGTTCAA
AAAGAAATTGCGTAAACTACAAGAAAATCCCTATATAGAATCTGCCAGATTACACGGTGATCTGGCGGGTTGTTTCAAAA
TCAAGTTGCGTTCGTCCGGTTTTCGTCTGGTCTATCAAGTGATAGATGAAGAAATCGTTATTTGGGTCATCGCTGTAGGT
AAACGAGAAGATTCAATGGCTTATGATATAGCCAAAAAACGTCTTGGTGTATGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT233208 WP_001288210.1 NZ_CP091347:c81254-80997 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT233208 NZ_FO818637:c323772-323518 [Xenorhabdus bovienii]
ATGAGCACTATTCAAGTAAGGGTTGATGAAGATCTGAAAAAGGCGTCTTACAAGGCTTTTGAAAAACTCAATGTGTCTCC
ATCTGACGCGTTGCGTCTGTTTCTGCGTTACGTTGCAGAGAATGAAAAACTGCCATTTTCTGAAGTATCGCTGATTGTGG
CTGAAAATGATAATGATGAAGATATTTTAGACGTTGTTCGTGAACGTATCAGAAATCCAGCCAAACGGGTTAGGGTTAAC
CTTGATGAAATTTAA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7