Detailed information of TA system TA233207

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3416056..3416709
• Replicon: chromosome
• Accession: NZ_CP091346
• Organism: Acinetobacter baumannii strain AB217-VUB

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: L2Z30_RS16765
• Protein ID: WP_000607077.1
• Coordinates: 3416056..3416445 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: L2Z30_RS16770
• Protein ID: WP_001288210.1
• Coordinates: 3416452..3416709 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2Z30_RS16750 (L2Z30_16750)	3411174..3413369	-	2196	WP_001158906.1	TRAP transporter large permease subunit	-
L2Z30_RS16755 (L2Z30_16755)	3413557..3414123	-	567	WP_000651538.1	rhombosortase	-
L2Z30_RS16760 (L2Z30_16760)	3414201..3415286	-	1086	WP_000049106.1	hypothetical protein	-
L2Z30_RS16765 (L2Z30_16765)	3416056..3416445	-	390	WP_000607077.1	membrane protein	Toxin
L2Z30_RS16770 (L2Z30_16770)	3416452..3416709	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
L2Z30_RS16775 (L2Z30_16775)	3416897..3418069	+	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
L2Z30_RS16780 (L2Z30_16780)	3418118..3419608	-	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
L2Z30_RS16785 (L2Z30_16785)	3419790..3420167	-	378	WP_064894046.1	50S ribosomal protein L17	-
L2Z30_RS16790 (L2Z30_16790)	3420186..3421193	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T233207 WP_000607077.1 NZ_CP091346:c3416445-3416056 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T233207 NZ_FO818637:158699-158989 [Xenorhabdus bovienii]
ATGCCACGTTTGATCTGGTCTCCGGCAGCCCTTACTGACGTACAAAAGCTCTATCGTTTTCTAGTCAATAAAGATGAAGC
AGCAGCTCGCAGAGCTATAAAAACAATACGTGCCAGCGTGAAAATTTTGGCTCACCAGCCTGAAGTAGGACGCCCTGCTG
AAGATATGGATCCCGTATTCCGAGAATGGCTTATTGATTTTGGTAGCAGTGGCTATATCGCCTTGTATCGTTTTGATGGT
GAAACAGCCACAATTCTTGCGGTGCGGCACCAAAAAGAAGCGGGATACTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT233207 WP_001288210.1 NZ_CP091346:c3416709-3416452 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT233207 NZ_FO818637:158439-158711 [Xenorhabdus bovienii]
ATGGCGACATCAGTAAAACTTGACGATAATTTAAAAAGCCGGATCCAGCATTTGGCAGAAGTTCGCCAGCGTTCGGCTCA
CTGGATAATGCGTGAAGCTATACGTGATTATGTAGAGCGTGAAGAAAAACGTGAGTCCTTCAAACAGGATGCATTGCGAG
CTTGGGAAGCGTATCAAGAGAATGGGTTACACCTGACACTTGAAGAAGCCGACGACTGGTTAGTAAAGCTCGAAGCAGGA
GATGATACGGAGTTACCTGAATGCCACGTTTGA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7