Detailed information of TA system TA233202

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3067650..3068303
• Replicon: chromosome
• Accession: NZ_CP091343
• Organism: Acinetobacter baumannii strain AB222-VUB

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: L2Z33_RS14725
• Protein ID: WP_000607077.1
• Coordinates: 3067650..3068039 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: L2Z33_RS14730
• Protein ID: WP_001288210.1
• Coordinates: 3068046..3068303 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2Z33_RS14710 (L2Z33_14710)	3062768..3064963	-	2196	WP_001158906.1	TRAP transporter large permease subunit	-
L2Z33_RS14715 (L2Z33_14715)	3065151..3065717	-	567	WP_000651538.1	rhombosortase	-
L2Z33_RS14720 (L2Z33_14720)	3065795..3066880	-	1086	WP_000049106.1	hypothetical protein	-
L2Z33_RS14725 (L2Z33_14725)	3067650..3068039	-	390	WP_000607077.1	membrane protein	Toxin
L2Z33_RS14730 (L2Z33_14730)	3068046..3068303	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
L2Z33_RS14735 (L2Z33_14735)	3068491..3069663	+	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
L2Z33_RS14740 (L2Z33_14740)	3069712..3071202	-	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
L2Z33_RS14745 (L2Z33_14745)	3071384..3071761	-	378	WP_001216380.1	50S ribosomal protein L17	-
L2Z33_RS14750 (L2Z33_14750)	3071780..3072787	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T233202 WP_000607077.1 NZ_CP091343:c3068039-3067650 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T233202 NZ_FO704551:c492406-492203 [Xenorhabdus poinarii G6]
ATGACTAAAATTGACTATCTGATGCGTTTGAGAAAATGCACCTCTATTGAAACATTGGAACGTGTAATTGAAAAAAATAA
ATATGAGCTTTCGGATGATGAACTAGAGTTGTTCTACTCTGCCGCAGATCACCGTTTAGCTGAACTGACTATGAACAAAC
TTTATGATAAAATTCCATCATCTGTTTGGAAATTTGTCCGTTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT233202 WP_001288210.1 NZ_CP091343:c3068303-3068046 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT233202 NZ_FO704551:c492823-492455 [Xenorhabdus poinarii G6]
ATGGACGAATATTCACCAAGAAAATATGATATCGCTGAATTAAAATACTTATGTGAAAATTTAATTGATGAAGCGCTCTC
AGTCCTGAATCGCACTGATAATCATTGGATTCACGATCTGACCTCCGAAAAAAGCTTAAAACTAAACGAATTGATGGAAC
ACATTGCAGCTTTTGTATTGAGTTTCAAAATTAAATACTCAGATAACTACACGCTAAGTACCTTAATTGATAACTATCTT
GATGAAACATATAATTTGTTTGGAAATGATAAGATAAGTTTTCTTGAACTGACGAAATGGCAAAGAACAAACGAACACTT
AACTAAGATCCTGTTACATGATTTGAACACTTCTTTAAGCAAAACCTGA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7