Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 735524..735669 Replicon chromosome
Accession NZ_CP091330
Organism Klebsiella pneumoniae strain CRK3022

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 735560..735662 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 735524..735669 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3Y35_RS03335 730654..732714 + 2061 WP_004151449.1 oligopeptidase B -
L3Y35_RS03340 732718..733377 - 660 WP_020324964.1 exodeoxyribonuclease X -
L3Y35_RS03345 733456..733686 - 231 WP_002911406.1 DNA polymerase III subunit theta -
L3Y35_RS03350 733799..734173 + 375 WP_004151448.1 CopC domain-containing protein YobA -
L3Y35_RS03355 734177..735046 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
L3Y35_RS03360 735063..735401 + 339 WP_002911404.1 YebY family protein -
- 735524..735669 - 146 - - Antitoxin
- 735560..735662 + 103 - - Toxin
L3Y35_RS03365 736038..736181 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
L3Y35_RS03370 736286..737254 - 969 WP_004151446.1 VirK/YbjX family protein -
L3Y35_RS03375 737411..738064 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
L3Y35_RS03380 738061..738252 - 192 WP_002911395.1 YebW family protein -
L3Y35_RS03385 738350..738589 - 240 WP_002911393.1 YebV family protein -
L3Y35_RS03390 738705..740138 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T233166 NZ_CP091330:735560-735662 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT233166 NZ_CP091330:c735669-735524 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References