Detailed information of TA system TA233161

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 451668..452321
• Replicon: chromosome
• Accession: NZ_CP091328
• Organism: Acinetobacter baumannii strain BM2333

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: L3Q73_RS02205
• Protein ID: WP_000607077.1
• Coordinates: 451932..452321 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: L3Q73_RS02200
• Protein ID: WP_001288210.1
• Coordinates: 451668..451925 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L3Q73_RS02180 (L3Q73_02180)	447184..448191	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
L3Q73_RS02185 (L3Q73_02185)	448210..448587	+	378	WP_001216380.1	50S ribosomal protein L17	-
L3Q73_RS02190 (L3Q73_02190)	448769..450259	+	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
L3Q73_RS02195 (L3Q73_02195)	450308..451480	-	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
L3Q73_RS02200 (L3Q73_02200)	451668..451925	+	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
L3Q73_RS02205 (L3Q73_02205)	451932..452321	+	390	WP_000607077.1	membrane protein	Toxin
L3Q73_RS02210 (L3Q73_02210)	453091..454176	+	1086	WP_000049106.1	hypothetical protein	-
L3Q73_RS02215 (L3Q73_02215)	454254..454820	+	567	WP_000651538.1	rhombosortase	-
L3Q73_RS02220 (L3Q73_02220)	455008..457203	+	2196	WP_001158906.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T233161 WP_000607077.1 NZ_CP091328:451932-452321 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T233161 NZ_CP128548:c3482270-3481866 [Pseudomonas kurunegalensis]
ATGCTGAAGTACATGCTTGATACCAACATGTGCATTTTCACGATCAAGAATCGTCCTGAGCAGGTGCGGGAAGCCTTCAA
GCGCCATTCAGGGCAGCTGAGCATCAGCACTGTCACCCTGATGGAGCTTATTTACGGCGCCGAGAAGTCCGCTAATCCCG
AGCGTAATCTGGCGGACGTTGAAGGTTTCGCTGCGCGCCTGGAAGTACTGCCTTACGACGCTCAGGCAGCGGCTCATTCC
GGGCAATTGCGAGCTGAGTTGGCTCGTATCGGCAAGCCTATTGGCCCGTATGATCAGATGATTGCAGGACACGCACGTGC
CCAGGGACTGATTCTGGTCACGAATAATCTTCGTGAATTCGAGCGAGTCCCAGGTTTGCGCGTCGAGGATTGGGTGAGTG
CCTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT233161 WP_001288210.1 NZ_CP091328:451668-451925 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT233161 NZ_CP128548:c3482500-3482270 [Pseudomonas kurunegalensis]
ATGGAACAAGGTGCAGTTTTTCAGAGCAACCGCAGTCAGGCGGTGCGTTTGCCCAAGGCGGTTGCGCTGCCTGAGGATGT
GAAGCGGGTGGATGTAGTGGTAGTTGGTCGAGCCCGAATCATCACGCCGGCAGGCGAGGCCTGGGACGTCTGGTTCGATG
GCGAAGGTGTGACCGCTGACTACATGGCGGATCGCGAGCAGCCTGCAGATCAAGAGCGGGATGCGTTCTGA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7