Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2251307..2251452 | Replicon | chromosome |
| Accession | NZ_CP091326 | ||
| Organism | Klebsiella pneumoniae strain hvK2115 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2251314..2251416 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2251307..2251452 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L3Y29_RS11110 | 2246839..2248272 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| L3Y29_RS11115 | 2248388..2248627 | + | 240 | WP_002911393.1 | YebV family protein | - |
| L3Y29_RS11120 | 2248725..2248916 | + | 192 | WP_002911395.1 | YebW family protein | - |
| L3Y29_RS11125 | 2248913..2249566 | - | 654 | WP_004891053.1 | protein-serine/threonine phosphatase | - |
| L3Y29_RS11130 | 2249723..2250691 | + | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| L3Y29_RS11135 | 2250796..2250939 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 2251307..2251452 | + | 146 | - | - | Antitoxin |
| - | 2251314..2251416 | - | 103 | - | - | Toxin |
| L3Y29_RS11140 | 2251575..2251913 | - | 339 | WP_002911404.1 | YebY family protein | - |
| L3Y29_RS11145 | 2251930..2252799 | - | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| L3Y29_RS11150 | 2252803..2253177 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| L3Y29_RS11155 | 2253290..2253520 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| L3Y29_RS11160 | 2253599..2254258 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| L3Y29_RS11165 | 2254262..2256322 | - | 2061 | WP_004151449.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T233143 NZ_CP091326:c2251416-2251314 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT233143 NZ_CP091326:2251307-2251452 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
