Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mazEF/PemK-MazE |
| Location | 3229506..3230020 | Replicon | chromosome |
| Accession | NZ_CP091318 | ||
| Organism | Methylocystis sp. SB2 | ||
Toxin (Protein)
| Gene name | mazF | Uniprot ID | - |
| Locus tag | LNB28_RS15710 | Protein ID | WP_029650264.1 |
| Coordinates | 3229694..3230020 (+) | Length | 109 a.a. |
Antitoxin (Protein)
| Gene name | mazE | Uniprot ID | - |
| Locus tag | LNB28_RS15705 | Protein ID | WP_026223051.1 |
| Coordinates | 3229506..3229694 (+) | Length | 63 a.a. |
Genomic Context
Location: 3224798..3225634 (837 bp)
Type: Others
Protein ID: WP_239755481.1
Type: Others
Protein ID: WP_239755481.1
Location: 3225804..3226688 (885 bp)
Type: Others
Protein ID: WP_036241769.1
Type: Others
Protein ID: WP_036241769.1
Location: 3227694..3229373 (1680 bp)
Type: Others
Protein ID: WP_029650266.1
Type: Others
Protein ID: WP_029650266.1
Location: 3229506..3229694 (189 bp)
Type: Antitoxin
Protein ID: WP_026223051.1
Type: Antitoxin
Protein ID: WP_026223051.1
Location: 3229694..3230020 (327 bp)
Type: Toxin
Protein ID: WP_029650264.1
Type: Toxin
Protein ID: WP_029650264.1
Location: 3230072..3230944 (873 bp)
Type: Others
Protein ID: WP_029650262.1
Type: Others
Protein ID: WP_029650262.1
Location: 3232025..3233155 (1131 bp)
Type: Others
Protein ID: WP_029650256.1
Type: Others
Protein ID: WP_029650256.1
Location: 3233148..3234071 (924 bp)
Type: Others
Protein ID: WP_239754230.1
Type: Others
Protein ID: WP_239754230.1
Location: 3234113..3234808 (696 bp)
Type: Others
Protein ID: WP_029650252.1
Type: Others
Protein ID: WP_029650252.1
Location: 3226685..3227581 (897 bp)
Type: Others
Protein ID: WP_029650268.1
Type: Others
Protein ID: WP_029650268.1
Location: 3230950..3231375 (426 bp)
Type: Others
Protein ID: WP_029650260.1
Type: Others
Protein ID: WP_029650260.1
Location: 3231372..3231881 (510 bp)
Type: Others
Protein ID: WP_051381759.1
Type: Others
Protein ID: WP_051381759.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LNB28_RS15685 (LNB28_15685) | 3224798..3225634 | + | 837 | WP_239755481.1 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | - |
| LNB28_RS15690 (LNB28_15690) | 3225804..3226688 | + | 885 | WP_036241769.1 | outer membrane protein assembly factor BamD | - |
| LNB28_RS15695 (LNB28_15695) | 3226685..3227581 | - | 897 | WP_029650268.1 | alpha/beta hydrolase | - |
| LNB28_RS15700 (LNB28_15700) | 3227694..3229373 | + | 1680 | WP_029650266.1 | DNA repair protein RecN | - |
| LNB28_RS15705 (LNB28_15705) | 3229506..3229694 | + | 189 | WP_026223051.1 | antitoxin MazE family protein | Antitoxin |
| LNB28_RS15710 (LNB28_15710) | 3229694..3230020 | + | 327 | WP_029650264.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
| LNB28_RS15715 (LNB28_15715) | 3230072..3230944 | + | 873 | WP_029650262.1 | chorismate mutase | - |
| LNB28_RS15720 (LNB28_15720) | 3230950..3231375 | - | 426 | WP_029650260.1 | type II toxin-antitoxin system VapC family toxin | - |
| LNB28_RS15725 (LNB28_15725) | 3231372..3231881 | - | 510 | WP_051381759.1 | hypothetical protein | - |
| LNB28_RS15730 (LNB28_15730) | 3232025..3233155 | + | 1131 | WP_029650256.1 | histidinol-phosphate transaminase | - |
| LNB28_RS15735 (LNB28_15735) | 3233148..3234071 | + | 924 | WP_239754230.1 | prephenate/arogenate dehydrogenase family protein | - |
| LNB28_RS15740 (LNB28_15740) | 3234113..3234808 | + | 696 | WP_029650252.1 | class I SAM-dependent methyltransferase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 109 a.a. Molecular weight: 11403.25 Da Isoelectric Point: 5.0322
>T233122 WP_029650264.1 NZ_CP091318:3229694-3230020 [Methylocystis sp. SB2]
MRRGAFVVVATSGDYGKPRPALVVQSDLFAELPSVVICPLTTTLRGDADLFRLDVEPSAGNGLRQASQIAVDKLTVVPSS
KIGEVIGEADDALLLRVNRALALFLGIV
MRRGAFVVVATSGDYGKPRPALVVQSDLFAELPSVVICPLTTTLRGDADLFRLDVEPSAGNGLRQASQIAVDKLTVVPSS
KIGEVIGEADDALLLRVNRALALFLGIV
Download Length: 327 bp
>T233122 NZ_CP128532:c800586-800362 [Mannheimia haemolytica]
ATGGTAGTAAAAATCCTAAAGCGGAAATCTCAAAAGACACTACAACAAATCTACACCCAGCCTATTTCTGCCAATATTAA
ATGGACAAATATAGAAGCTCTTTTTCTAGAGTTAGGAGCAGAAATAGAAGAACGAGAAGGGAGCAGAATTGCAGTTGTTT
TATTTCAACAGGTCAGAGTATTTCATCGCCCACACCCGAATCCTGATACAGATAAGGGGCGGTAG
ATGGTAGTAAAAATCCTAAAGCGGAAATCTCAAAAGACACTACAACAAATCTACACCCAGCCTATTTCTGCCAATATTAA
ATGGACAAATATAGAAGCTCTTTTTCTAGAGTTAGGAGCAGAAATAGAAGAACGAGAAGGGAGCAGAATTGCAGTTGTTT
TATTTCAACAGGTCAGAGTATTTCATCGCCCACACCCGAATCCTGATACAGATAAGGGGCGGTAG
Antitoxin
Download Length: 63 a.a. Molecular weight: 7174.16 Da Isoelectric Point: 6.4497
>AT233122 WP_026223051.1 NZ_CP091318:3229506-3229694 [Methylocystis sp. SB2]
MASYRQRMRAAGLRPVQIWAPDSRAPDFIEKCHRQARAVAIHDPAGDEIMQFVASMYEWPED
MASYRQRMRAAGLRPVQIWAPDSRAPDFIEKCHRQARAVAIHDPAGDEIMQFVASMYEWPED
Download Length: 189 bp
>AT233122 NZ_CP128532:c800319-799990 [Mannheimia haemolytica]
ATGCGTAATATTATGGATATTAATGGTTATAAAGCTGTCATTGCTTACGATCCCGAAACAGAATTATTTCGAGGTGAATT
TATCGGATTAAATGGTGGAGCCGATTTTTATGCCGATAATGTCATTCAATTAAAAAAAGAAGGTGAACTAAGTTTGAATA
TCTTTTTAGAACTTTGTAGAGAAAAAGGTATTGAGCCGTTCAAACAATATTCCGGAAAGTTTAATGTTCGCCTTTCGCCT
GAATTACATAAAGCTGCGGTAATTGCAGCAACTGCTGAAAATTTAAGCTTAAATGAATGGATTAACCAAACGTTAGAAAA
GAGCGTGTAG
ATGCGTAATATTATGGATATTAATGGTTATAAAGCTGTCATTGCTTACGATCCCGAAACAGAATTATTTCGAGGTGAATT
TATCGGATTAAATGGTGGAGCCGATTTTTATGCCGATAATGTCATTCAATTAAAAAAAGAAGGTGAACTAAGTTTGAATA
TCTTTTTAGAACTTTGTAGAGAAAAAGGTATTGAGCCGTTCAAACAATATTCCGGAAAGTTTAATGTTCGCCTTTCGCCT
GAATTACATAAAGCTGCGGTAATTGCAGCAACTGCTGAAAATTTAAGCTTAAATGAATGGATTAACCAAACGTTAGAAAA
GAGCGTGTAG