Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) slvAT/RES(toxin)
Location 1058320..1059242 Replicon chromosome
Accession NZ_CP091317
Organism Lysobacter soli strain RCu6

Toxin (Protein)


Gene name slvT Uniprot ID -
Locus tag L3D22_RS04755 Protein ID WP_253337404.1
Coordinates 1058320..1058865 (-) Length 182 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID -
Locus tag L3D22_RS04760 Protein ID WP_192632808.1
Coordinates 1058862..1059242 (-) Length 127 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3D22_RS04745 (L3D22_04740) 1053839..1055065 + 1227 WP_253337401.1 efflux RND transporter periplasmic adaptor subunit -
L3D22_RS04750 (L3D22_04745) 1055075..1058242 + 3168 WP_253337403.1 efflux RND transporter permease subunit -
L3D22_RS04755 (L3D22_04750) 1058320..1058865 - 546 WP_253337404.1 RES family NAD+ phosphorylase Toxin
L3D22_RS04760 (L3D22_04755) 1058862..1059242 - 381 WP_192632808.1 DUF2384 domain-containing protein Antitoxin
L3D22_RS04765 (L3D22_04760) 1059436..1059852 - 417 WP_157031215.1 phasin family protein -
L3D22_RS04770 (L3D22_04765) 1060042..1062330 + 2289 WP_253337406.1 patatin-like phospholipase family protein -
L3D22_RS04775 (L3D22_04770) 1062355..1062708 - 354 WP_253337408.1 6-carboxytetrahydropterin synthase QueD -
L3D22_RS04780 (L3D22_04775) 1062802..1063728 + 927 WP_253337410.1 S41 family peptidase -
L3D22_RS04785 (L3D22_04780) 1063864..1064226 + 363 WP_253337411.1 BON domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(12-167)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 182 a.a.        Molecular weight: 19691.14 Da        Isoelectric Point: 4.8367

>T233119 WP_253337404.1 NZ_CP091317:c1058865-1058320 [Lysobacter soli]
MILRELGDGDALYRVIVPRWSHAPTSGAGAARKGGRFNRPGLEALYLSKDAITALEEYRQHELLLPPGTLVTFLVGPLVV
VDFSAGFDSARWEPIWADYACNWRRLAFDERSEPPSWVLGDIALDAGAAGILFPSSAHAGGTNLVLFNSSELPARMLRVH
DPDGHLPGDARSWGDADDARD

Download         Length: 546 bp

>T233119 NZ_CP128532:c25018-24590 [Mannheimia haemolytica]
ATGTATCGCTACCTTTTTGATACCAATATAGTTTCCGAGCTTTATAAGTTAAGAAATGACAAGATGGATGTCAATGTTCG
CCAGTGGCTGAGAGGGGTTAATCCTAGCCAGACCAATATCAGCTGTATTACGTTATCTGAAATCAAAACAGGTATTTTGC
TGAAAGCCCGCAAAGACAAAGAACAATCAGACCGATTAAATGATTGGTTTGAAAATAATGTATTAAAGGCTTATCAAACA
AAAGCGTTTGTGGTGAATAACGACATTGCTCTATTGGCATCAGAGTACCATATTCCCAATAAAATGGATTTAAATGATGC
TTATATTGCGGCAACCGCCAAATACCACAATCTGATTTTAGTCACCCGCAACACCAAAGATTTTATCCGTTGTGATGTGC
GTTTATTTAACCCATTTGAAACCGCATAA

Antitoxin


Download         Length: 127 a.a.        Molecular weight: 13716.45 Da        Isoelectric Point: 5.1515

>AT233119 WP_192632808.1 NZ_CP091317:c1059242-1058862 [Lysobacter soli]
MNAVMKSRASLAEAVREPDQVYLSPRRIGDALGLQVQSLAERARVSRNTPTARPQNEHLQQYLRDVVRVIAAAEDAAGGD
RTRAIFWFMNDPLADFDYLTADALVQAGKAQVVIDYIESVAGGATG

Download         Length: 381 bp

>AT233119 NZ_CP128532:c25305-25018 [Mannheimia haemolytica]
ATGGCAATAACCATTACTTCCAGAGAATTTAATCAAAATGCCAGCAAAGTGTTAAAAATGGCAGAAAAAGAGCCGGTTTT
TATTACCAAATGGGGCAAAATCGTCAATGTGGTGTCTAGTTATATGGATTATCAGCAGAAAAAGCCTAGCGAGCCAAGCT
TTGAAGAGCTATTCGCCTCTTCCGAAAATGAGGATGTGAGCGATGAATTTTGGCAAGAGTTTGAACAAACATTGGTTGAA
ATCCGCAAAAGCAATAAACCAAGACCTGTTGATTTTGGAGATGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References