Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 31422..31927 Replicon chromosome
Accession NZ_CP091244
Organism Thiothrix winogradskyi strain CT3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L2Y54_RS00185 Protein ID WP_236498999.1
Coordinates 31422..31679 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L2Y54_RS00190 Protein ID WP_093064688.1
Coordinates 31670..31927 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2Y54_RS00160 (L2Y54_00160) 27267..27878 + 612 WP_236498993.1 SCO family protein -
L2Y54_RS00165 (L2Y54_00165) 27953..28540 - 588 WP_236498995.1 Fe-Mn family superoxide dismutase -
L2Y54_RS00170 (L2Y54_00170) 28646..29833 - 1188 WP_236498996.1 hypothetical protein -
L2Y54_RS00175 (L2Y54_00175) 29897..30139 + 243 WP_236498997.1 hypothetical protein -
L2Y54_RS00180 (L2Y54_00180) 30306..31412 + 1107 WP_236498998.1 PEGA domain-containing protein -
L2Y54_RS00185 (L2Y54_00185) 31422..31679 - 258 WP_236498999.1 Txe/YoeB family addiction module toxin Toxin
L2Y54_RS00190 (L2Y54_00190) 31670..31927 - 258 WP_093064688.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
L2Y54_RS00195 (L2Y54_00195) 32061..33086 - 1026 WP_236499001.1 hypothetical protein -
L2Y54_RS00200 (L2Y54_00200) 33115..33774 - 660 WP_236499002.1 hypothetical protein -
L2Y54_RS00205 (L2Y54_00205) 34056..35833 + 1778 Protein_40 N-acetylglutaminylglutamine amidotransferase -
L2Y54_RS00210 (L2Y54_00210) 36233..36583 - 351 WP_236499004.1 type II toxin-antitoxin system prevent-host-death family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10229.78 Da        Isoelectric Point: 9.4094

>T233061 WP_236498999.1 NZ_CP091244:c31679-31422 [Thiothrix winogradskyi]
MRIIFSSKAWEDYVHWQQADKKILKRINDLIKAISRDPFDGIGKPEPLRHGLSGYWSRRINDEHRLVYKLEGEDLLIAMC
RYHYQ

Download         Length: 258 bp

>T233061 NZ_CP128525:c25018-24590 [Mannheimia haemolytica]
ATGTATCGCTACCTTTTTGATACCAATATAGTTTCCGAGCTTTATAAGTTAAGAAATGACAAGATGGATGTCAATGTTCG
CCAGTGGCTGAGAGGGGTTAATCCTAGCCAGACCAATATCAGCTGTATTACGTTATCTGAAATCAAAACAGGTATTTTGC
TGAAAGCCCGCAAAGACAAAGAACAATCAGACCGATTAAATGATTGGTTTGAAAATAATGTATTAAAGGCTTATCAAACA
AAAGCGTTTGTGGTGAATAACGACATTGCTCTATTGGCATCAGAGTACCATATTCCCAATAAAATGGATTTAAATGATGC
TTATATTGCGGCAACCGCCAAATACCACAATCTGATTTTAGTCACCCGCAACACCAAAGATTTTATCCGTTGTGATGTGC
GTTTATTTAACCCATTTGAAACCGCATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9655.99 Da        Isoelectric Point: 4.4118

>AT233061 WP_093064688.1 NZ_CP091244:c31927-31670 [Thiothrix winogradskyi]
MNAISYTAVRADLAKTMDRVCEDHEPVIITRNREQAVVMISLEDYKAMEETAYLLRSPANASRLLESIAELERGQGQVRE
LIECE

Download         Length: 258 bp

>AT233061 NZ_CP128525:c25305-25018 [Mannheimia haemolytica]
ATGGCAATAACCATTACTTCCAGAGAATTTAATCAAAATGCCAGCAAAGTGTTAAAAATGGCAGAAAAAGAGCCGGTTTT
TATTACCAAATGGGGCAAAATCGTCAATGTGGTGTCTAGTTATATGGATTATCAGCAGAAAAAGCCTAGCGAGCCAAGCT
TTGAAGAGCTATTCGCCTCTTCCGAAAATGAGGATGTGAGCGATGAATTTTGGCAAGAGTTTGAACAAACATTGGTTGAA
ATCCGCAAAAGCAATAAACCAAGACCTGTTGATTTTGGAGATGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References