Detailed information of TA system TA232867

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3402513..3403166
• Replicon: chromosome
• Accession: NZ_CP091173
• Organism: Acinetobacter baumannii strain AB5116

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: A0A9E9PBS3
• Locus tag: L2M54_RS16330
• Protein ID: WP_002096593.1
• Coordinates: 3402513..3402902 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: L2M54_RS16335
• Protein ID: WP_001288210.1
• Coordinates: 3402909..3403166 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2M54_RS16315 (L2M54_16315)	3397631..3399826	-	2196	WP_001158905.1	TRAP transporter large permease subunit	-
L2M54_RS16320 (L2M54_16320)	3400014..3400580	-	567	WP_000651536.1	rhombosortase	-
L2M54_RS16325 (L2M54_16325)	3400658..3401743	-	1086	WP_000049106.1	hypothetical protein	-
L2M54_RS16330 (L2M54_16330)	3402513..3402902	-	390	WP_002096593.1	hypothetical protein	Toxin
L2M54_RS16335 (L2M54_16335)	3402909..3403166	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
L2M54_RS16340 (L2M54_16340)	3403354..3404526	+	1173	WP_001190548.1	acyl-CoA dehydrogenase family protein	-
L2M54_RS16345 (L2M54_16345)	3404575..3406065	-	1491	WP_004745487.1	NAD(P)/FAD-dependent oxidoreductase	-
L2M54_RS16350 (L2M54_16350)	3406247..3406624	-	378	WP_001216380.1	50S ribosomal protein L17	-
L2M54_RS16355 (L2M54_16355)	3406643..3407650	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15677.99 Da
• Isoelectric Point: 10.3890

>T232867 WP_002096593.1 NZ_CP091173:c3402902-3402513 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLVEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T232867 NZ_CP128416:187795-188100 [Rhizobium sp. CSC1952]
ATGAACGAGAAGCGGAAGGCGCACTGCCCGTTGGAAAGAGTGAAATCGCTTGTCAAAGCAGGTCAGGTCCGTACGACCTA
CTCCGCCTTGGCTGGCGCATCGCGGCTCGATTTCACGCTTTCCGAAATGTACGAGACGGTTCTGGCGTTGACCCTTACCG
ACTTTTACAAATCGATGACGACCTATGCCGACCACAAGGTCTGGCAGGATGTATATCGGCCGATGACGAAGGCGGGGCGG
ATTTATCTGAAACTGACCGTCGTCGATGACGTGCTGATCGTGTCCTTCAAGGAGTTGAACGAATGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT232867 WP_001288210.1 NZ_CP091173:c3403166-3402909 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT232867 NZ_CP128416:188097-188498 [Rhizobium sp. CSC1952]
ATGAAGTGCCCGGCTTGCGGTGAGGCAGAACTTTCCCGCCAGACCCGTGACTTGCCCTACTCCTATAAAGGGGAAGAGAC
CACGATCGCGAGTGTAACCGGTGATTTTTGCGCGGCCTGCGGCGAGATCGTTCTAGGCGACGCCGAAGCCAGGCGGATCA
ATGCCGCCATGCTGGAATTTAACAAGCAAGTGAACGCTGGCAGCGTCGATCCAGCGTTCGTGGCATCCGTTCGCAAGAAG
CTAAAGCTGGACCAGAAGGAAGCCGGCGACATTTTCGGCGGCGGCGTCAACGCGTTTTCCCGCTATGAAAACGGGAAAAC
GAAGCCTCCCGTGGCGTTGGTCAAGTTGTTGAAGCTTCTCGACAAACATCCCGAACTCCTTCAGGAAATTCGCGCGGCCT
GA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7