Detailed information of TA system TA232858

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 4596053..4596578
• Replicon: chromosome
• Accession: NZ_CP091147
• Organism: Pseudomonas avellanae strain NCPPB 4222

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: L2Y01_RS20820
• Protein ID: WP_081591631.1
• Coordinates: 4596339..4596578 (+)
• Length: 80 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: L2Y01_RS20815
• Protein ID: WP_024420242.1
• Coordinates: 4596053..4596298 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2Y01_RS20810 (L2Y01_20810)	4591969..4595880	-	3912	WP_024420241.1	ATP-dependent RNA helicase HrpA	-
L2Y01_RS20815 (L2Y01_20815)	4596053..4596298	+	246	WP_024420242.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
L2Y01_RS20820 (L2Y01_20820)	4596339..4596578	+	240	WP_081591631.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	Toxin
L2Y01_RS20825 (L2Y01_20825)	4596705..4598396	-	1692	WP_005619941.1	long-chain-fatty-acid--CoA ligase FadD1	-
L2Y01_RS20830 (L2Y01_20830)	4598752..4600489	-	1738	Protein_4112	long-chain fatty acid--CoA ligase	-
L2Y01_RS20835 (L2Y01_20835)	4600885..4601355	+	471	WP_005740134.1	MaoC family dehydratase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-66)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-69)

Sequences

Toxin

Protein

• Length: 80 a.a.
• Molecular weight: 8959.35 Da
• Isoelectric Point: 10.2637

>T232858 WP_081591631.1 NZ_CP091147:4596339-4596578 [Pseudomonas avellanae]
MGHTVSAQLKKKLLERLELPRNAGDALHGMPDHYKIKLRSAGYRLVYRVEDDRVVVTVVAVGKRERGDIYDSAKDRLSP

Nucleotide

• Length: 240 bp

>T232858 NZ_CP128389:2235054-2235263 [Staphylococcus aureus]
ATGATACATCAAAATACGATTTACACAGCGGGAATTGAAACAGAAGAACAAGTAAGTCAATTGACAGAACGCATTTCAAA
TATGATAGGTGTTCATCAAGTGAATATTAATATAATTGATGGTCAAGTAACGGTATCGTATGAGACACCAGCAAATTTGA
ATAGTATTGAAAAAGAAATTTATGATGAAGGATACAAAATTGTATTTTAG

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8861.32 Da
• Isoelectric Point: 4.4848

>AT232858 WP_024420242.1 NZ_CP091147:4596053-4596298 [Pseudomonas avellanae]
MQNIFADIAVSVSELKKNPSAVLSGAQGLPVAVLNHNKVMGYMVPAEVFEAMMERLDDLDLADLIKARQHEKPVSVDILD
L

Nucleotide

• Length: 246 bp

>AT232858 NZ_CP128389:2234749-2235042 [Staphylococcus aureus]
ATGACTGAACAAGATAATGCACATCATTCTGAACAAATAAAAACGAATCTTAAATCACGTTTAAATCGAATTGAAGGACA
AGTGAGAGCGATTAATCGCATGATTGAAGAAGATGTCTATTGTGATGATGTCCTTACGCAAATAAGAGCGACACGTTCGG
CGTTAAACAGTGTTGCGATAAAGTTATTAGAACAACATATGAAAAGTTGTATTATGAATAAAGTTAATCAAGGAGCTCAG
GAAGAGGCAATGGAAGAGTTATTAGTGACTTTTCAAAAATTGATTAAAGACTAA