Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 4547851..4548313 Replicon chromosome
Accession NZ_CP091147
Organism Pseudomonas avellanae strain NCPPB 4222

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L2Y01_RS20660 Protein ID WP_081591738.1
Coordinates 4548032..4548313 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L2Y01_RS20655 Protein ID WP_005622273.1
Coordinates 4547851..4548042 (+) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2Y01_RS20645 (L2Y01_20645) 4545903..4546214 - 312 WP_005616177.1 antibiotic biosynthesis monooxygenase family protein -
L2Y01_RS20650 (L2Y01_20650) 4546478..4547782 + 1305 WP_029768581.1 mechanosensitive ion channel family protein -
L2Y01_RS20655 (L2Y01_20655) 4547851..4548042 + 192 WP_005622273.1 hypothetical protein Antitoxin
L2Y01_RS20660 (L2Y01_20660) 4548032..4548313 + 282 WP_081591738.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L2Y01_RS20665 (L2Y01_20665) 4548763..4549473 + 711 WP_249741603.1 XopAF/AvrXv3 family type III secretion system effector -
L2Y01_RS20670 (L2Y01_20670) 4549780..4549984 - 205 Protein_4080 IS3 family transposase -
L2Y01_RS20675 (L2Y01_20675) 4550207..4551106 + 900 WP_024420134.1 hypothetical protein -
L2Y01_RS20680 (L2Y01_20680) 4551300..4551764 + 465 Protein_4082 AraC family transcriptional regulator -
L2Y01_RS20685 (L2Y01_20685) 4551887..4552234 - 348 WP_005619902.1 zinc ribbon domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10413.04 Da        Isoelectric Point: 8.0701

>T232857 WP_081591738.1 NZ_CP091147:4548032-4548313 [Pseudomonas avellanae]
MLVEWRPAARINLQQIPLYIADRNAQAASELGMAIEVATSALPQHPCLYRQGRVPGTREIVVHPNYLVVYRVTDRIEVLA
VLHARHAYPTDAG

Download         Length: 282 bp

>T232857 NZ_CP128389:700345-700533 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7043.78 Da        Isoelectric Point: 4.4184

>AT232857 WP_005622273.1 NZ_CP091147:4547851-4548042 [Pseudomonas avellanae]
MSARTSPIVSEFKTEEQAASYDKWFRAQVQASISDPAPNIPHDQVMAEMREFLESKQTPSDAG

Download         Length: 192 bp

>AT232857 NZ_CP128389:700057-700317 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATAGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References