Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2379942..2380455 Replicon chromosome
Accession NZ_CP091147
Organism Pseudomonas avellanae strain NCPPB 4222

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L2Y01_RS11095 Protein ID WP_081591612.1
Coordinates 2379942..2380226 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L2Y01_RS11100 Protein ID WP_005619468.1
Coordinates 2380216..2380455 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2Y01_RS11080 (L2Y01_11080) 2376088..2378016 + 1929 WP_024421321.1 methyl-accepting chemotaxis protein -
L2Y01_RS11085 (L2Y01_11085) 2378045..2378977 - 933 WP_024420854.1 DMT family transporter -
L2Y01_RS11090 (L2Y01_11090) 2379052..2379906 + 855 WP_005619469.1 LysR family transcriptional regulator -
L2Y01_RS11095 (L2Y01_11095) 2379942..2380226 - 285 WP_081591612.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L2Y01_RS11100 (L2Y01_11100) 2380216..2380455 - 240 WP_005619468.1 ribbon-helix-helix protein, CopG family Antitoxin
L2Y01_RS11105 (L2Y01_11105) 2380624..2381640 - 1017 WP_005619467.1 1-aminocyclopropane-1-carboxylate deaminase -
L2Y01_RS11110 (L2Y01_11110) 2381806..2382312 + 507 WP_005619465.1 winged helix-turn-helix transcriptional regulator -
L2Y01_RS11115 (L2Y01_11115) 2382461..2383369 + 909 WP_005619464.1 DUF808 domain-containing protein -
L2Y01_RS11120 (L2Y01_11120) 2384045..2384830 - 786 WP_003376153.1 outer membrane protein OmpK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-40)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10881.79 Da        Isoelectric Point: 10.6168

>T232854 WP_081591612.1 NZ_CP091147:c2380226-2379942 [Pseudomonas avellanae]
MQVEWLKTALKNLDDKAAYISLENPAAAVVFVEAIQISVKQLASFPALGREGRIAGSREWPLPDWPYLIPYRIRNGRLQV
LRIFHMRRQPPLVW

Download         Length: 285 bp

>T232854 NZ_CP128388:2259999-2260361 [Staphylococcus aureus]
ATGATTAGACGAGGAGATGTTTATTTAGCAGATTTATCACCAGTACAGGGATCTGAACAAGGGGGAGTCAGACCTGTAGT
CATAATTCAAAATGATACTGGTAATAAATATAGTCCTACAGTTATTGTTGCGGCAATAACTGGTAGGATTAACAAAGCGA
AAATACCGACACATGTAGAGATTGAAAAGAAAAAGTATAAATTGGATAAAGACTCAGTTATATTATTAGAGCAAATTCGT
ACACTTGATAAAAAACGATTGAAAGAAAAACTGACGTACTTATCCGATGATAAAATGAAAGAAGTAGATAATGCACTAAT
GATTAGTTTAGGGCTAAATGCAGTAGCTCATCAGAAAAATTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8726.87 Da        Isoelectric Point: 4.5822

>AT232854 WP_005619468.1 NZ_CP091147:c2380455-2380216 [Pseudomonas avellanae]
MSVMSLRLPDEMADTLAHLGKATGRSKSFLALNALREYLTREAWQIAEIQRAIEEADAGEFASEEDVKAVMNKWANTAG

Download         Length: 240 bp

>AT232854 NZ_CP128388:2259832-2260002 [Staphylococcus aureus]
ATGTTATCTTTTAGTCAAAATAGAAGTCATAGCTTAGAACAATCTTTAAAAGAAGGATATTCACAAATGGCTGATTTAAA
TCTCTCCCTAGCGAACGAAGCTTTTCCGATAGAGTGTGAAGCATGCGATTGCAACGAAACATATTTATCTTCTAATTCAA
CGAATGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References