Detailed information of TA system TA232843

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 5847481..5847943
• Replicon: chromosome
• Accession: NZ_CP091143
• Organism: Pseudomonas avellanae strain NCPPB 3491

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: L2Y00_RS26520
• Protein ID: WP_081591738.1
• Coordinates: 5847481..5847762 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: L2Y00_RS26525
• Protein ID: WP_005622273.1
• Coordinates: 5847752..5847943 (-)
• Length: 64 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2Y00_RS26490 (L2Y00_26490)	5843454..5843801	+	348	WP_005619902.1	zinc ribbon domain-containing protein	-
L2Y00_RS26495 (L2Y00_26495)	5843924..5844388	-	465	Protein_5234	AraC family transcriptional regulator	-
L2Y00_RS26500 (L2Y00_26500)	5844582..5845202	-	621	WP_024421473.1	hypothetical protein	-
L2Y00_RS26505 (L2Y00_26505)	5845354..5845695	-	342	WP_229687568.1	hypothetical protein	-
L2Y00_RS26510 (L2Y00_26510)	5845810..5846014	+	205	Protein_5237	IS3 family transposase	-
L2Y00_RS26515 (L2Y00_26515)	5846321..5847031	-	711	WP_249740234.1	XopAF/AvrXv3 family type III secretion system effector	-
L2Y00_RS26520 (L2Y00_26520)	5847481..5847762	-	282	WP_081591738.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
L2Y00_RS26525 (L2Y00_26525)	5847752..5847943	-	192	WP_005622273.1	hypothetical protein	Antitoxin
L2Y00_RS26530 (L2Y00_26530)	5848012..5848554	-	543	Protein_5241	mechanosensitive ion channel	-
L2Y00_RS26535 (L2Y00_26535)	5848877..5850292	+	1416	WP_005622278.1	gamma-mobile-trio recombinase GmtY	-
L2Y00_RS26540 (L2Y00_26540)	5850882..5851271	+	390	WP_024421445.1	hypothetical protein	-
L2Y00_RS26545 (L2Y00_26545)	5851293..5852309	+	1017	WP_005615738.1	IS30-like element ISPsy38 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	5851293..5852309	1016

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10413.04 Da
• Isoelectric Point: 8.0701

>T232843 WP_081591738.1 NZ_CP091143:c5847762-5847481 [Pseudomonas avellanae]
MLVEWRPAARINLQQIPLYIADRNAQAASELGMAIEVATSALPQHPCLYRQGRVPGTREIVVHPNYLVVYRVTDRIEVLA
VLHARHAYPTDAG

Nucleotide

• Length: 282 bp

>T232843 NZ_CP128261:4567919-4568230 [Salmonella enterica subsp. enterica serovar Heidelberg]
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACATTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGCACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATACTATCGGGGTAATAAAGAATGA

Antitoxin

Protein

• Length: 64 a.a.
• Molecular weight: 7043.78 Da
• Isoelectric Point: 4.4184

>AT232843 WP_005622273.1 NZ_CP091143:c5847943-5847752 [Pseudomonas avellanae]
MSARTSPIVSEFKTEEQAASYDKWFRAQVQASISDPAPNIPHDQVMAEMREFLESKQTPSDAG

Nucleotide

• Length: 192 bp

>AT232843 NZ_CP128261:4568227-4568673 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGAGAACTCATCGTCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAACCGTCCC
ACTGATGGGGGAAGACCGAAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATC
TTGAAAACCCACTATTTGAATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAATCACTCAAC
CAACACCTGGAGAAAACACCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCT
TGCCAACGAACTTGGTTCTAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATCAAAG
CGCTTACACAACGCTTTAAACTACCAGCGGATGCCTTCATCGAGTAG