Detailed information of TA system TA232842

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 5794051..5794576
• Replicon: chromosome
• Accession: NZ_CP091143
• Organism: Pseudomonas avellanae strain NCPPB 3491

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: L2Y00_RS26310
• Protein ID: WP_081591631.1
• Coordinates: 5794051..5794290 (-)
• Length: 80 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: L2Y00_RS26315
• Protein ID: WP_005619938.1
• Coordinates: 5794331..5794576 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2Y00_RS26295 (L2Y00_26295)	5789323..5789793	-	471	WP_005740134.1	MaoC family dehydratase	-
L2Y00_RS26300 (L2Y00_26300)	5790189..5791877	+	1689	WP_005619943.1	long-chain-fatty-acid--CoA ligase FadD2	-
L2Y00_RS26305 (L2Y00_26305)	5792233..5793924	+	1692	WP_005619941.1	long-chain-fatty-acid--CoA ligase FadD1	-
L2Y00_RS26310 (L2Y00_26310)	5794051..5794290	-	240	WP_081591631.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	Toxin
L2Y00_RS26315 (L2Y00_26315)	5794331..5794576	-	246	WP_005619938.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
L2Y00_RS26320 (L2Y00_26320)	5794749..5798660	+	3912	WP_024420241.1	ATP-dependent RNA helicase HrpA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-66)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 80 a.a.
• Molecular weight: 8959.35 Da
• Isoelectric Point: 10.2637

>T232842 WP_081591631.1 NZ_CP091143:c5794290-5794051 [Pseudomonas avellanae]
MGHTVSAQLKKKLLERLELPRNAGDALHGMPDHYKIKLRSAGYRLVYRVEDDRVVVTVVAVGKRERGDIYDSAKDRLSP

Nucleotide

• Length: 240 bp

>T232842 NZ_CP128261:c4566686-4566375 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGAGGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8842.27 Da
• Isoelectric Point: 4.4830

>AT232842 WP_005619938.1 NZ_CP091143:c5794576-5794331 [Pseudomonas avellanae]
MQNIFADIAVSVSELKKNPSAVLSGAQGLPVAVLNHNKVMGYMVPAEVFEAMMEHLDDLDLADLIKARQHEKPVSVDILD
L

Nucleotide

• Length: 246 bp

>AT232842 NZ_CP128261:c4566374-4566084 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGGATAAAGTGTTATTTGAGCGATTAACTCAAAGTATGTCTCAAATGAATGAAATCATTGAAGGGACCCGTGAGCCTTC
TCGTACCTTTCATATTGATGCAATGAAGATTAAAGAAATACGGCAGGCATCTGGGTTGTCGCAATCTAAGTTTGCAGAAC
TGATTTCGGTCAACGTGGATACGCTGCGCAACTGGGAGCAAGGAAGACGTTCACCGACAGGGCCAGCCAAAGCGTTACTT
CGCGCCATTGCCAACGACCCGAGAAACGTTATACAAGCATTGCGTTATTGA