Detailed information of TA system TA232839

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 3012082..3012623
• Replicon: chromosome
• Accession: NZ_CP091143
• Organism: Pseudomonas avellanae strain NCPPB 3491

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A0Q0ECV1
• Locus tag: L2Y00_RS13470
• Protein ID: WP_024419858.1
• Coordinates: 3012348..3012623 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: L2Y00_RS13465
• Protein ID: WP_081591395.1
• Coordinates: 3012082..3012348 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2Y00_RS13450 (L2Y00_13450)	3007365..3007628	+	264	WP_005615061.1	hypothetical protein	-
L2Y00_RS13455 (L2Y00_13455)	3007756..3009636	-	1881	WP_024419856.1	methyl-accepting chemotaxis protein	-
L2Y00_RS13460 (L2Y00_13460)	3009995..3011917	+	1923	WP_024419857.1	methyl-accepting chemotaxis protein	-
L2Y00_RS13465 (L2Y00_13465)	3012082..3012348	+	267	WP_081591395.1	ribbon-helix-helix domain-containing protein	Antitoxin
L2Y00_RS13470 (L2Y00_13470)	3012348..3012623	+	276	WP_024419858.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
L2Y00_RS13475 (L2Y00_13475)	3013195..3014463	+	1269	WP_005615053.1	OprD family porin	-
L2Y00_RS13480 (L2Y00_13480)	3014643..3015470	+	828	WP_005615050.1	NAD(P)-dependent oxidoreductase	-
L2Y00_RS13485 (L2Y00_13485)	3015527..3016411	+	885	WP_005615047.1	SMP-30/gluconolactonase/LRE family protein	-
L2Y00_RS13490 (L2Y00_13490)	3016468..3017493	+	1026	WP_005615044.1	TRAP transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (8-45)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10710.40 Da
• Isoelectric Point: 7.0121

>T232839 WP_024419858.1 NZ_CP091143:3012348-3012623 [Pseudomonas avellanae]
MELMWTSKALSDVARLYDFLAVANQPAAAQTVQKLTAAPIMLLSNPRIGERLEEFEPRDVRKIQIGRYEMRYEIVDSTIY
LLRLWHTREDR

Nucleotide

• Length: 276 bp

>T232839 NZ_CP128261:3635723-3635986 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGAATGCCTCCGGCGCCAGCGTCCGCCACATCAACAGCGAAACCTGCATGACCACCTGTTACTCACAAATCCCCAGCGG
CGACTGCCAGGAAGAAGCGGGATTTGAGACCGGGGCGAGCGTTGTTGTGAAGATCTCCGAGCGGGGTTTGATCCTGATTG
CAGAAACGGATGAAGTGAGGGATCTACGGAAGGAGCTTTATCAGGTGAAAAAGTCGATGAAGCATATTAAGGCGGGGGTA
AATAATGTGGTGAACGGGAATTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9948.23 Da
• Isoelectric Point: 5.7066

>AT232839 WP_081591395.1 NZ_CP091143:3012082-3012348 [Pseudomonas avellanae]
MTTKTRSVTAHVPEQLAEKVDLMAERLERSKNWIVRQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSLST
ATPLPVPR

Nucleotide

• Length: 267 bp

>AT232839 NZ_CP128261:c3635976-3635566 [Salmonella enterica subsp. enterica serovar Heidelberg]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCATCCGTTTCTGCAATCAGGATCAAACCCCGCTCGGAGATCTTCACAACAACGCTCGCCCCGGTCTCAAATCCCGCTT
CTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGTGGTCATGCAGGTTTCGCTGTTGATGTGGCGGACGCTGGCG
CCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTGAG
CGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCCGG
GGCCGTATTTT

Structures

Toxin

• AlphaFold DB: A0A0Q0ECV1