Detailed information of TA system TA232838

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 2339759..2340272
• Replicon: chromosome
• Accession: NZ_CP091143
• Organism: Pseudomonas avellanae strain NCPPB 3491

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: L2Y00_RS10350
• Protein ID: WP_081591612.1
• Coordinates: 2339988..2340272 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: L2Y00_RS10345
• Protein ID: WP_005619468.1
• Coordinates: 2339759..2339998 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2Y00_RS10325 (L2Y00_10325)	2335384..2336169	+	786	WP_003376153.1	outer membrane protein OmpK	-
L2Y00_RS10330 (L2Y00_10330)	2336845..2337753	-	909	WP_005619464.1	DUF808 domain-containing protein	-
L2Y00_RS10335 (L2Y00_10335)	2337902..2338408	-	507	WP_005619465.1	winged helix-turn-helix transcriptional regulator	-
L2Y00_RS10340 (L2Y00_10340)	2338574..2339590	+	1017	WP_005619467.1	1-aminocyclopropane-1-carboxylate deaminase	-
L2Y00_RS10345 (L2Y00_10345)	2339759..2339998	+	240	WP_005619468.1	ribbon-helix-helix protein, CopG family	Antitoxin
L2Y00_RS10350 (L2Y00_10350)	2339988..2340272	+	285	WP_081591612.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
L2Y00_RS10355 (L2Y00_10355)	2340308..2341162	-	855	WP_005619469.1	LysR family transcriptional regulator	-
L2Y00_RS10360 (L2Y00_10360)	2341237..2342169	+	933	WP_024420854.1	DMT family transporter	-
L2Y00_RS10365 (L2Y00_10365)	2342198..2344126	-	1929	WP_024421321.1	methyl-accepting chemotaxis protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-40)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10881.79 Da
• Isoelectric Point: 10.6168

>T232838 WP_081591612.1 NZ_CP091143:2339988-2340272 [Pseudomonas avellanae]
MQVEWLKTALKNLDDKAAYISLENPAAAVVFVEAIQISVKQLASFPALGREGRIAGSREWPLPDWPYLIPYRIRNGRLQV
LRIFHMRRQPPLVW

Nucleotide

• Length: 285 bp

>T232838 NZ_CP128261:3407372-3407590 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8726.87 Da
• Isoelectric Point: 4.5822

>AT232838 WP_005619468.1 NZ_CP091143:2339759-2339998 [Pseudomonas avellanae]
MSVMSLRLPDEMADTLAHLGKATGRSKSFLALNALREYLTREAWQIAEIQRAIEEADAGEFASEEDVKAVMNKWANTAG

Nucleotide

• Length: 240 bp

>AT232838 NZ_CP128261:3406970-3407344 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAGGGCCAATCCTGTTAGTTTGTCTTGTTAA