Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2339759..2340272 Replicon chromosome
Accession NZ_CP091143
Organism Pseudomonas avellanae strain NCPPB 3491

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L2Y00_RS10350 Protein ID WP_081591612.1
Coordinates 2339988..2340272 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L2Y00_RS10345 Protein ID WP_005619468.1
Coordinates 2339759..2339998 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2Y00_RS10325 (L2Y00_10325) 2335384..2336169 + 786 WP_003376153.1 outer membrane protein OmpK -
L2Y00_RS10330 (L2Y00_10330) 2336845..2337753 - 909 WP_005619464.1 DUF808 domain-containing protein -
L2Y00_RS10335 (L2Y00_10335) 2337902..2338408 - 507 WP_005619465.1 winged helix-turn-helix transcriptional regulator -
L2Y00_RS10340 (L2Y00_10340) 2338574..2339590 + 1017 WP_005619467.1 1-aminocyclopropane-1-carboxylate deaminase -
L2Y00_RS10345 (L2Y00_10345) 2339759..2339998 + 240 WP_005619468.1 ribbon-helix-helix protein, CopG family Antitoxin
L2Y00_RS10350 (L2Y00_10350) 2339988..2340272 + 285 WP_081591612.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L2Y00_RS10355 (L2Y00_10355) 2340308..2341162 - 855 WP_005619469.1 LysR family transcriptional regulator -
L2Y00_RS10360 (L2Y00_10360) 2341237..2342169 + 933 WP_024420854.1 DMT family transporter -
L2Y00_RS10365 (L2Y00_10365) 2342198..2344126 - 1929 WP_024421321.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-40)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10881.79 Da        Isoelectric Point: 10.6168

>T232838 WP_081591612.1 NZ_CP091143:2339988-2340272 [Pseudomonas avellanae]
MQVEWLKTALKNLDDKAAYISLENPAAAVVFVEAIQISVKQLASFPALGREGRIAGSREWPLPDWPYLIPYRIRNGRLQV
LRIFHMRRQPPLVW

Download         Length: 285 bp

>T232838 NZ_CP128261:3407372-3407590 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8726.87 Da        Isoelectric Point: 4.5822

>AT232838 WP_005619468.1 NZ_CP091143:2339759-2339998 [Pseudomonas avellanae]
MSVMSLRLPDEMADTLAHLGKATGRSKSFLALNALREYLTREAWQIAEIQRAIEEADAGEFASEEDVKAVMNKWANTAG

Download         Length: 240 bp

>AT232838 NZ_CP128261:3406970-3407344 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAGGGCCAATCCTGTTAGTTTGTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References