Detailed information of TA system TA232831

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-RHH
• Location: 2091829..2092352
• Replicon: chromosome
• Accession: NZ_CP091138
• Organism: Microbacterium sp. KUDC0406

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: L2X99_RS10480
• Protein ID: WP_236123672.1
• Coordinates: 2091829..2092122 (-)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: L2X99_RS10485
• Protein ID: WP_236123671.1
• Coordinates: 2092119..2092352 (-)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2X99_RS10440 (L2X99_10440)	2087404..2087916	-	513	WP_236135070.1	PqqD family protein	-
L2X99_RS10445 (L2X99_10445)	2087853..2088758	-	906	WP_236135071.1	hypothetical protein	-
L2X99_RS10450 (L2X99_10450)	2088810..2089076	-	267	WP_236135072.1	hypothetical protein	-
L2X99_RS10455 (L2X99_10455)	2089066..2089377	-	312	WP_236123675.1	type IV toxin-antitoxin system AbiEi family antitoxin	-
L2X99_RS10460 (L2X99_10460)	2089415..2090125	-	711	WP_236135073.1	hypothetical protein	-
L2X99_RS17900	2090356..2091785	+	1430	Protein_2068	excalibur calcium-binding domain-containing protein	-
L2X99_RS10480 (L2X99_10480)	2091829..2092122	-	294	WP_236123672.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
L2X99_RS10485 (L2X99_10485)	2092119..2092352	-	234	WP_236123671.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
L2X99_RS10490 (L2X99_10490)	2092812..2093268	-	457	Protein_2071	ISL3 family transposase	-
L2X99_RS10495 (L2X99_10495)	2093436..2094341	-	906	WP_236123670.1	hypothetical protein	-
L2X99_RS10500 (L2X99_10500)	2094568..2095722	-	1155	WP_236135074.1	hypothetical protein	-
L2X99_RS10505 (L2X99_10505)	2096046..2097320	-	1275	WP_236123668.1	oligosaccharide flippase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2082579..2098437	15858
	-	flank	IS/Tn	-	-	2092786..2093268	482

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-93)

Antitoxin

• Antitoxin ParD (4-72)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 11275.68 Da
• Isoelectric Point: 5.6391

>T232831 WP_236123672.1 NZ_CP091138:c2092122-2091829 [Microbacterium sp. KUDC0406]
VIDYRLSPAAQRDLSSIWDYTLERWDESQAETDVLEIRAAIERIAAQPERGRPVDEIRGGYWRYSIGSHLIFFVERPGGG
VDVIRILHQRMDPTRHV

Nucleotide

• Length: 294 bp

>T232831 NZ_CP128260:c6328853-6328575 [Pseudomonas fluorescens]
ATGATCGTTAGCTTCAGATGTTCTGAAACCGAATACCTGTTCCGTAGCGGTAAAACCCGTTTCTGGTCAGCCATATTGAG
TGTCGCGGAACGTAAGCTGACGATGCTTGATGCGGCAGCTGTGTTGGCTGATCTTCGGTCTCCTCCGGGAAATCGACTGG
AGACCCTGGAAGGTGATCGAAAGGGGCAATACAGCATCCGGATCAATGCTCAATGGCGAATTTGCTTCGTCTGGGGCCTT
AATGGTCCTGAGGATGTTGAAATCGTCGATTATCACTGA

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 8394.22 Da
• Isoelectric Point: 4.3077

>AT232831 WP_236123671.1 NZ_CP091138:c2092352-2092119 [Microbacterium sp. KUDC0406]
MASNTSISLDEHFTDFLAQEVATGRYRSASEVVRAGLRLLEDHESQMSVLRASLAAGEESGEPEAFDFDAFIASKRA

Nucleotide

• Length: 234 bp

>AT232831 NZ_CP128260:c6328567-6328262 [Pseudomonas fluorescens]
ATGACTAAGAATGGTATGCGTCCGGTCCATCCCGGCGAGATCCTCAAAGAGGAGTACCTGGAACCTCTGAGCCTTACAGC
TGCTGCGTTGGCGAGAGCATTGAGTGTGTCTACTCCAACGGTGAACGACATTGTTCTACAGCGACGAGGTATCAGCGCTG
ATATGGCGTTAAGGCTTTCAATCTGCCTGGATACCACTCCCGAGTTTTGGCTGAACCTGCAATCGACTTACGATTTGCGA
AAAGCTGAAATTGAGAGAGGAGCTTCCATCCGTGATCAAGTGGAGCGGCTGGCGCATTGCGCTTGA